在PTAS组中,不同责任血管的主要结果发生率存在显著差异[ICA(26.67)>BA(17.17)> MCA(8.28)>VA(4.76)]。 在PTAS组和药物治疗组比较中,ICA、MCA和VA狭窄患者的主要结果无明显差异。 然而,BA狭窄患者接受PTAS治疗的风险更高[17.17% vs. 7.77%; 9.40,HR, 2.38(1.03~5.52),P=0.043]。白种人[HR,4.24(1.17-15....
研究目的:探究在ICA终末段±MCA M1段血管急性闭塞中,抽吸联合拉栓 vs 拉栓,谁是更好的一线治疗方式。 方法 研究设计:RCT(ASTER2)研究的亚组分析 纳入人群:ICA终末段±MCA M1段血管急性闭塞 造影指标:首过效应,eTICI≥2b50 ...
Introduction The neutrophil-lymphocyte ratio (NLR) as an inexpensive and easily available inflammatory marker, has become a useful index in various conditions such as cardiovascular diseases, neoplastic diseases, diabetes, and recently acute ischemic stroke (AIS). We studied the association between the ...
CAMs do express TGF-β in naïve conditions (https://anratherlab.shinyapps.io/strokevis/). In our model, CAM depletion leads to a decreased aneurysm formation and rupture rate. Our data suggests a potential role of CAM-derived TGF-β as a triggering factor for aneurysm formation and ...
Stroke attracts neutrophils to the injured brain tissue where they can damage the integrity of the blood–brain barrier and exacerbate the lesion. How
(MCA) of the ipsilateral hemisphere. Classical vascular analysis for vessel density, junctional branch points, total end points, and average and total vessel length were obtained using the Fiji plugin, Angiotool [45]. Analysis focused on lesion and perilesional regions (see Fig.4A). Fractal ...
, UH3 NS100121 and RF1 NS110048 from National Institute of Neurological Disorders and Stroke (J.F.A-V. and D.S-F)., Alzheimer’s Association Research Fellowship (C.V.C), Comité para el Desarrollo de la Investigación (CODI) of Universidad de Antioquia (F.L.), Fapesp Grant 2019/...
Odds of thrombectomy were determined by multivariate logistic regression to account for hospital type, geographic location, and patient demographics.Results: Between 2015–2019 we identified a total of 1,721,207 stroke patients, of whom 12,620 patients had a BAO and 137,118 had ICA/MCA ...
Flow in the MCA on the symptomatic and asymptomatic side was decreased when at least one ICA was occluded. Total cerebropetal flow (flow through the ICAs plus basilar artery) was decreased when at least one ICA was occluded. No significant correlation was found between changes in cerebropetal ...
and improved neurological function. Given that inflammatory cells actively contribute to secondary brain injury after stroke [1], we speculate that the attenuated neurological injury is due to milder vascular damage. In support of this possibility, extravasated neutrophils have been demonstrated to contri...