Cells expressing ionized calcium binding adapter molecule 1 (Iba1), a specific marker of microglia/macrophages, increased in number in the virally infected region of the trigeminal ganglion, with morphological transformation to an activated phenotype, frequently detected as perineural satellites. Further ...
Flow cytometric analysis of SH-SY5Y cells (blue) and THP-1 cells (green) using Iba1/AIF-1 (E4O4W) XP® Rabbit mAb (PE Conjugate) (solid lines) or a concentration-matched Rabbit (DA1E) mAb IgG XP® Isotype Control (PE Conjugate) #57...
Immunofluorescence analysis of IBA1 was performed using 70% confluent log phase THP-1 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled...
Background:Allograft Inflammatory Factor-1 (AIF1)or ionized calcium-binding adaptor molecule 1 (Iba1) is expressed selectively in microglia/macrophages and is a Ca2+-binding peptide produced by activated monocytes and microglial cells. It has been suggested that AIF1 expression is associated with ch...
Iba1 is a 17-kDa EF hand protein that is specifically expressed in macrophages/microglia and is upregulated during the activation of these cells. When exposed to macrophage colony-stimulating factor (M-CSF), microglia cell line MG5 immediately produces intense membrane ruffles in which Iba1 accumu...
Iba1(Ionized calcium-binding adapter molecule 1)是分子量约为17 kDa的钙结合蛋白。由于在中枢神经系统中,Iba1在小胶质细胞中特异性表达1),因此被用作小胶质细胞标志物。据报告称,Iba1在静息型小胶质细胞和活化型小胶质细胞中均有表达,但有报告称在活化型小胶质细胞中其表达会有所增加2)。另外,Iba1也会在外...
Anti-Iba1/AIF1 Antibody, clone 16B14, ZooMAb® Rabbit Monoclonal recombinant, expressed in HEK 293 cells; Synonyms: Anti-AIF-1,Anti-IBA1,Anti-IRT-1,Anti-IRT1 at Sigma-Aldrich
While the involvement of microglia, immune cells that play an important role in brain inflammation, has recently been suggested not only in neurodegenerative diseases but also in various other neurops… 4th review: Macrophages control the inflammation and subsequent neural repair after ischemic strokeWak...
Immunofluorescence analysis of IBA1 was performed using 70% confluent log phase THP-1 cells. The cells were fixed with 4% paraformaldehyde for 15 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled...
“Gene expression profile of human mesenchymal stem cells during osteogenesis in three-dimensional thermoreversible gelation polymer”Biochem. Biophys. Res.Commun.,317, 1103-1107 (2004). 8.人类肝细胞3-D培养生产丙型肝炎病毒(HCV) “Production of infectious hepatitis C virus particles in three-dimensiona...