Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease process that leads to variable clinical presentations and outcomes. Many individuals with HCM will remain asymptomatic or only mildly symptomatic throughout life and require no medical intervention. Identification and treatment of symptomatic and ...
Hypertrophic cardiomyopathy accounts for 36% of deaths in athletes younger than 35 (most common cause of sudden death in this age group). Most sudden deaths are due to ventricular fibrillation (VF) or ventricular tachycardia (VT) (see fig. 61). These patients should avoid competitive sports bec...
Hypertrophic cardiomyopathy is a serious disease that affects the muscles of the heart. This leads to the thickening of the heart chambers (particularly the ventricles), stiffness of the left ventricles, and problems with the mitral valve(the valve between the left atriumand left ventricle). There...
Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac disorders and is characterized by different phenotypes of left ventricular hype
Hypertrophic cardiomyopathy (HCM) is a form of primary myocardial hypertrophy, with or without presence of left ventricular outflow tract (LVOT) obstruction; it is characterized by four cardinal features: Idiopathic LV hypertrophy (LVH) in absence of other cardiac or systemic disease causing hypertroph...
Hypertrophic cardiomyopathy (HCM) is a genetic heart disease that is associated with many pathological features, such as a reduction in global longitudinal strain (GLS), myofiber disarray and hypertrophy. The effects of these features on left ventricle (
Hypertrophic cardiomyopathy (HCM) is the most common of all genetic heart diseases and is the leading cause of sudden cardiac death. It is characterized by an abnormal thickening of the heart muscle, which over time can lead to cardiac dysfunction, and u
Hypertrophic cardiomyopathy (HCM) is the most common genetic (autosomal dominant) cardiovascular disease, the incidence is 0.2% in the general adult population but fre- quently unrecognized, and is the most common cause of sudden cardiac death (SCD) in the young. HCM can pres- ent clinically ...
Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease in the U.S. Learn more about what causes it and who’s at risk.
This study investigated whether missense cardiac myosin-binding protein C gene (MYBPC3) mutation in hypertrophic cardiomyopathy (HCM) leads to destabilization of its protein, causes UPS impairment, and is associated with cardiac dysfunction. Mutations were identified in Japanese HCM patients using ...