Hypertrophic cardiomyopathy (HCM) is a global disease with cases reported in all continents, affecting people of both genders and of various racial and ethnic origins. Widely accepted as a monogenic disease caused by a mutation in 1 of 13 or more sarcomeric genes, HCM can present catastrophically...
Thick and heavy hearts had been of interest and investigation to physicians and pathologists for many centuries. This article reviews the early history of hypertrophic cardiomyopathy and reflects on several centuries of progress in our understanding of the condition. ...
ContextThroughout the past 40 years, a vast and sometimes contradictory literature has accumulated regarding hypertrophic cardiomyopathy (HCM), a genetic
Article CAS PubMed Google Scholar Maron BJ . Hypertrophic cardiomyopathy: a systematic review. JAMA 2002; 287:1308–20. PubMed Google Scholar Jarcho JA, McKenna WJ, Pare JAP, et al. Mapping a gene for familial hypertrophic cardiomyopathy to chromosome 14q1. N Engl J Med 1989; 321:1372...
Review of Hypertrophic Cardiomyopathyhypertrophycardiomyopathyagegene polymorphismHypertrophic obstructive cardiomyopathy (HOCM) has had a long history and many different names. Probably the first descriptions of HOCM were by Liouvielle in 1869 [1] and Hallopeau [2] in the same journal. Schminke [3]...
Given the velocity of progress in both the fields of heart failure and HCM, we present a review of the approach to patients with HCM, with particular attention to those with HCM and the clinical syndrome of heart failure. 展开 关键词: hypertrophic cardiomyopathy heart failure LV hypertrophy ...
Nature Cardiovascular Research volume 1, pages 445–461 (2022)Cite this article 2400 Accesses 27 Altmetric Metrics details Abstract Hypertrophic cardiomyopathy (HCM) is a common inherited cardiovascular disease with heterogeneous clinical presentations, governed by multiple molecular mechanisms. Metabolic ...
Hypertrophic cardiomyopathy (HCM) is a primary disorder of the cardiac muscle characterized by inappropriate myocardial hypertrophy of a nondilated left ventricle (LV) in the absence of a cardiovascular or systemic disease (i.e., aortic stenosis or systemic hypertension). ...
Hypertrophic cardiomyopathy (HCM) is a congenital cardiac disease with an estimated prevalence of 1:500 in the population. Individuals with HCM can present with clinical manifestations that include left ventricular outflow obstruction, cardiac dysrhythmias, diastolic heart failure, cardiac angina, and sud...
Electronic supplementary material Below is the link to the electronic supplementary material. Cite this article Chiang, Y.P., Shimada, Y.J., Ginns, J.et al.Septal myectomy for hypertrophic cardiomyopathy: important surgical knowledge and technical tips in the era of increasing alcohol septal ablatio...