Hypertrophic cardiomyopathy (HCM) is a common, serious, genetic heart disorder. Rare pathogenic variants in sarcomere genes cause HCM, but with unexplained phenotypic heterogeneity. Moreover, most patients do no
Background Since 2018 NHS Ayrshire and Arran (NHSA&A) has offered a specialist nurse-led hypertrophic cardiomyopathy (HCM) clinic, providing assessment and education to those with clinically stable HCM, and those genetically at risk of HCM. Though there is growing evidence on the safety of ...
The right ventricle (RV) in hypertrophic cardiomyopathy (HCM) tends to be neglected, as previous efforts have predominantly focused on examining the prognostic value of left ventricular (LV) abnormalities. The objectives of this study were to assess RV function in HCM, changes over time, and asso...
Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiovascular disease that affects approximately one in 500 people. HCM is a recognized genetic disorder most often caused by mutations involving myosin-binding protein C (MYBPC3) and β-myosin heavy chain (MYH7) which are responsible fo...
In the present study, we aimed to examine the value of native and post-contrast T1 relaxation in the differentiation of healthy and diffusely diseased myocardium in 2 model conditions, hypertrophic cardiomyopathy (HCM) and nonischemic dilated cardiomyopathy (NIDCM). Download: Download high-res ...
The incidence of sustained VA requiring device therapy was higher however, in the FD cohort compared to both the HCM cohort and previous studies of subjects with non-ischemic cardiomyopathy [6], thus suggesting that device implantation in FD is delayed until the disease is more advanced or ...
Hypertrophic cardiomyopathy (HCM) is defined by unexplained hypertrophy and often characterized by diastolic and systolic dysfunction. HCM patients are known to have impaired left ventricular (LV) myocardial work (MW), a more load-independent parameter compared to global longitudinal strain (GLS). We ...
Background In 2017 the West of Scotland Inherited Cardiac Conditions (ICC) service received British Heart Foundation funding to develop local nurse-led hypertrophic cardiomyopathy (HCM) clinics across Scotland, including within NHS Ayrshire and Arran (NHSA&A). Those with stable HCM, and family ...
cardiomyopathy, hypertrophicdiagnostic imagingHypertrophic cardiomyopathy (HCM) is the most frequently cited cause of exercise-related sudden cardiac death (SCD) in young individuals and has claimed the lives of some high-profile athletes. The circumstantial link between exercise and SCD from HCM has ...
Hypertrophic cardiomyopathyUnited KingdomSurvivalAetiologyAims Understanding the spectrum of disease, symptom burden and natural history are essential for the management of children with hypertrophic cardiomyopathy (HCM). The effect of changing screening practices over time has not previously been studied. ...