T cell–expressed HVEM is required for accumulation of large populations of memory CD8 T cells.Rachel FlynnTarun HutchinsonKenneth M. MurphyCarl F. WareMichael CroftShahram SalekArdakani
TCM central memory T cell TCR T cell receptor TEM effector memory T cell TEMRA effector memory T cell re-expressing CD45RA TN naïve T cell TRAF2 TNF receptor associated factor 2 VPD450 violet proliferation dye 450 1. Introduction The highly functioning immune system is a warranty of immune...
Our experiments proved that HVEM exerted its immunosuppressive effect by inhibiting antitumour function of CD8+T cell through CRD1 domain both in vivo and in vitro. Additionally, we identified a combination therapy capable of completely eradicating ALL tumours, which induces immune memory toward tumour...
16P Checkpoint modification of BTLA-HVEM-LIGHT signaling by HSV-1 glycoprotein D (gD) improves vaccine-induced CD8+ T cell responses in pre-clinical cancer modelsdoi:10.1016/j.annonc.2022.01.024A. LuberX. ZhouZ. XiangW. Giles-DavisC. Magowan...