HDGEC status (carrier versus control) was related to DNA methylation data in three different species:ahuman blood,bmouse striatum/cerebellum, andcsheep blood. Each Manhattan plot reports minus log10-transformedpvalues (y-axis) versus chromosomal location. Each dot corresponds to a CpG. CpGs near...
Two consultations in a single day at the metropolitan center, phone counseling, and attendance at nonmetropolitan out- reach clinics were measures adopted to meet the needs of rural candidates. Asymptomatic status was not always clinically con- firmed because some candidates declined the neurologic ex...
2 Pagon RA, Tarczy-Hornoch P, Baskin PK et al: GeneTests-GeneClinics: genetic testing information for a growing audience. Hum Mutat 2002; 19: 501–509. 3 Ross CA, Tabrizi SJ: Huntington's disease: from molecular pathogenesis to clinical treatment. Lancet Neurol 2011; 10: 83–98. 4 ...