The present invention is directed to novel human DNA sequences encoding a voltage-gated potassium channel, KCNQ5, located in a chromosomal region that contains a gene associated with Stargardt-like macular dystrophy, cone-rod macular dystrophy, and Salla disease.PETRUKHIN KONSTANTIN...
摘要: We studied tone in the human ductus arteriosus and show that the constriction to oxygen is due to inhibition of voltage-gated potassium channels and, in the acute phase, is independent of endothelin-1.关键词: HIV-infection travel medicine counselling tropical diseases prophylaxis vaccination ...
中文名称:人电压门控钾通道抗体(VGKC-AB)抗体ELISA KIT 中文同义词:人电压门控钾通道抗体(VGKC-AB)抗体ELISA KIT 英文名称:Human voltage-gated potassium channel antibody (VGKC-AB) antibody ELISA KIT 英文同义词: CAS号: 分子式: 分子量:0 EINECS号: ...
channel transfectionEndogenous voltage-gated potassium currents were investigated in human embryonic kidney (HEK293) and Chinese hamster ovary (CHO) cells using whole-cell voltage clamp recording. Depolarizing voltage steps from 70 mV triggered an outwardly rectified current in nontransfected HEK293 cells...
Article: Voltage-gated potassium channels do not set the membrane potential of CCRF-CEM, a human T lymphoblastoid cell line
detecting, a method of screening for inhibitors and potassium channel activators used (eg, Kv10.1) and Kv10 subfamily biologically active members, and Kv10 subfamily members (eg, Kv10.1) and, The invention provides methods for screening for activators and inhibitors of voltage-gated potassium ...
Recently, human β-defensin 2 and fungal plectasin were shown to be immune-related potassium voltage-gated channel subfamily A member 3 (Kv1.3) channel inhibitors. This work continued to show that the human α-defensins human neutrophil peptide (HNP) 1 and human defensin (HD) 5 are selective...
We found that the voltage-gated potassium channel (KV) modifier KCNG4 (KV6.4) SNP rs140124801 rare allele c.1255G>A p.(Val419Met) was over-represented. Finally, we demonstrate the effects of this rare KV6.4-Met419 variant on sensory neuron excitability and reveal a mechanism through which...
Voltage-gated potassium conductance in human T lymphocytes stimulated with phorbol ester. The whole-cell patch-clamp method was used to study the voltage-gated K+ conductance of human peripheral blood T lymphocytes. After entry into whole-cell r... Deutsch,C,Krause,... - 《Journal of ...
voltage‐gated ion channelhKv1.5 channelvolatile anestheticsdesfluranesevofluranemechanismsite‐directed mutagenesisBackground and purpose: Volatile anesthetics have been shown to differentially modulate mammalian Shaker-related voltage-gated potassium (Kv1) channels. This study was designed to investigate ...