Differentiation of CD4+effector cells into the Th2 lineage is promoted by cytokines such as IL-4 in combination with either IL-2, IL-7, or TSLP. Th2 cells secrete IL-4, IL-5, IL-9, IL-13, and IL17E/IL-25. The CellXVivo™ Human Th2 Cell Differentiation Kit contains all ...
RATIONALE: Murine IL-27 is a potent suppressor of Th2 cell differentiation. However, it is unknown whether murine IL-27 suppresses Th2 cytokine production by differentiated Th2 cells and if so which signaling pathway murine IL-27 uses. Moreover, it is unclear if human IL-27 suppresses Th2...
英文名称:CellXVivo Human Th2 Cell Differentiation Kit (1 KT) 英文同义词:CellXVivo Human Th2 Cell Differentiation Kit (1 KT) CAS号: 分子式: 分子量:0 EINECS号: 信息错误报告 您的Email: 按国家浏览CellXVivo Human Th2 Cell Differentiation Kit (1 KT)国外供应商中国供应商 ...
DIFFERENTIATION GENE REGULATION IN IMMUNE CELLS SYSTEMS BIOLOGY CELL SIGNALLING Received 27 April 2012 Accepted 1 June 2012 Published 18 June 2012 Gene Set Enrichment Analysis Identifies LIF as a Negative Regulator of Human Th2 Cell Differentiation Ubaid Ullah1, Parul Tripathi1, Riitta Lahesmaa2 & ...
regulating the expression of T cell trafficking genes, and production of Th2 cytokines. Within the CD8+ T cell subset, IL-2 is essential for optimal primary responses and differentiation into terminal effector cells. IL-2 also promotes the development of activated CD8+ T cells into memory cells...
Th1 Differentiation Profile. View Larger ImageFigure 2. Naïve T Cells were isolated from PBMCs using the MagCellect Human Naïve CD4+T Cell Isolation Kit (Catalog #MAGH115). These cells were either untreated (Th0) or treated with Human Th1-inducing reagents; Mouse Anti-...
In our experiments, we observed rapid internalization of Mala s13 and hTrx upon cell contact and we were able to confirm direct interaction with Dectin-1 as well as Dectin-2 applying a fusion protein screening platform. We hypothesize that this cytokine response may result in a Th2/Th17-...
myeloid differentiation / proliferation CD117 c-kit, SCFR 145kD IgSF, RTK family hematopoietic progenitors, mast cells SCF receptor, hematopoietic progenitor development / differentiation CD118 LIFR, gp190 190kD Type I CRSF & secre...
Migratory LCs are more efficient than CD1c+DDCs at priming naive CD4+ T cells to produce both Th1 and Th2 cytokines We then analyzed the ability of LCs and CD1c+DDCs to support allogeneic naive CD4+ T-cell differentiation. To this end, naive CD4+ T cells were co-cultured with LCs or...
Representative dot plots (e) and statistical evaluation of the differentiation into Th1 (IFNγ+) cells (f), Th2 (IL-4+) cells (g), and Th17 (IL-17A+) cells (h) after 6 days of coculture (n = 5 individual T cell donors). Intracellular cytokine expression was analyzed after ...