were released to the scientific community as the largest collection of proteomic data to date. The first addition of normal protein ranges based on the UKB data on Olink Insight contains data on approximately 1,500 proteins, while the second pha...
The proteome database provided here may be of future use in advancing understanding of ethnic differences in the T lymphocyte response to immunotherapeutic drugs. Access through your organization Check access to the full text by signing in through your organization. Access through your organization ...
Since plasma does not undergo coagulation, it takes less time to collect, and it contains the additional clotting proteins that are not present in serum. Plasma can be collected from blood, and it contains approximately 10–20% more proteins than serum due to the presence of the clotting ...
Extensive genomic characterization of human cancers presents the problem of inference from genomic abnormalities to cancer phenotypes. To address this problem, we analysed proteomes of colon and rectal tumours characterized previously by The Cancer Genom
The plasma proteome database contains concentration information for a large set of proteins. We extracted these proteins with concentration and divided them into 10 equal bins. In each bin, protein percentage identified in our dataset are highlighted (e.g. 99% in the top bin). b Plot of ...
On the basis of large proteomics datasets measured from seven human cell lines we consider their intersection as an approximation of the human central proteome, which is the set of proteins ubiquitously expressed in all human cells. Composition and properties of the central proteome are investigated ...
Proteomes are characterized by large protein-abundance differences, cell-type- and time-dependent expression patterns and post-translational modifications, all of which carry biological information that is not accessible by genomics or transcriptomics. H
While it is possible that the EVs released by embryonic and adult MSCs preferentially enclose different miRNA forms, conditioned medium as a whole presumably contains heterogeneous populations of RNA when compared with exosomes purified by differential ultracentrifugation, as analyzed in this study. ...
Even the approximately 16.5 kb of DNA left in the mitochondria of humans participate either as a whole or in parts in an ongoing transfer and integration into the nuclear DNA [90]. A similar picture is painted by viral encounters with humans. Viruses, especially retroviruses, proliferate through...
Uncoated precut emitters (Silica Tip, 20 μm inner diameter, 10 μm tip inner diameter; New Objectives) and a voltage of approximately 2.6 kV were applied for ESI. The secretome sample was obtained by precipitation of hiPSC culture supernatants that were separated by SDS-PAGE and digested ...