Human Pangenome Reference Consortium - HG002 Data Freeze (v1.0) - human-pangenomics/HG002_Data_Freeze_v1.0
ODGI. GitHub https://github.com/pangenome/odgi (2021). Shlemov, A. & Korobeynikov, A. in Algorithms for Computational Biology (eds Holmes, I., Martín-Vide, C. & Vega-Rodríguez, M. A.) 80–94 (Springer, 2019). Ebler, J. et al. Pangenome-based genome inference. Preprint at...
Jupyter Notebooks Using PGR-TK for various human pangenome analysis tasks (see https://github.com/Sema4-Research/pgr-tk/blob/main/README.md) 00-0-setup.ipynb # optional setup for the computing environment 00-1-create_pgr_index.ipynb # note for creating the pgr-tk index 01-read_and_quer...
Human Pangenome Reference Consortium - HG002 Data Freeze (v1.0) - tongwang666/HG002_Data_Freeze_v1.0
Wang T. The Human Pangenome Project: a global resource to map genomic diversity. Nature, 2022. Nurk, et al. The complete sequence of a human genome. Science, 2022. Zook J. et al. A robust benchmark for detection of germline large deletions and insertions. Nature Biotechnology, 2022. Ass...
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals1. These assemblies cover more than 99% of the expected sequence in each genome and are more ...
Here the Human Pangenome Reference Consortium presents a first draft of the human pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of genetically diverse individuals1. These assemblies cover more than 99% of the expected sequence in each genome and are more ...
For any problems related to this dataset, please raiseissueson this GitHub repository. For general questions regarding the project, please contactadam.phillippy@nih.gov. More information about our consortium can be found on theT2T homepage.
File? hprc_af Allele frequences in ~100 Human Pangenome Reference Consortium (HPRC) samples in slivar gnotate format required if run_tertiary_analysis is set to true File? gff Ensembl GFF3 reference annotation required if run_tertiary_analysis is set to true Array[IndexData?] population_vcfs...
Human papillomavirus (HPV) drives almost all cervical cancers and up to 70% of head and neck cancers. Frequent integration into the host genome occurs predominantly in tumorigenic types of HPV. We hypothesize that changes in chromatin state at the l