Genetics is increasingly becoming a part of modern medical practice. How people think about genetics’ use in medicine and their daily lives is therefore essential. Earlier studies indicated mixed attitudes about genetics. However, this might be changing. Using the preferred reporting items for systema...
Despite the research efforts, a definitive function has not been established for the majority of NCL proteins. 2. NCL proteins 2.1. CLN1 (palmitoyl protein thioesterase 1) Mutations of the CLN1 gene cause infantile CLN1 disease, which is the most severe form of NCLs, presents in children at...
The review is divided into six sections: (1) compendia of data resources; (2) biomolecular repository “Hubs”; (3) a list of cancer-related data resources, which provides information on contents of the resource and whether the resource enables upload and analysis of investigator provided data;...
The viral RNA genome is released into the cytoplasm; after replication of the viral genome, genomic RNA accompanied by envelope glycoproteins and nucleocapsid proteins forms virion-containing vesicles, which then fuse with the plasma membrane to release the virus [13]. The first genomic sequence of...
COVID-19 is an emergent disease with many unknown aspects of its pathogenesis, and the main therapeutic approaches [8], consist of immunotherapies and antivi- ral drugs. Notwithstanding, the absence of a single spe- cific antiviral therapy for CoV resides in its novelty since COVID-19 was ...
auris increases globally, it is important to raise awareness to prevent transmission and hospital outbreaks. Keywords: Candida auris; antifungal resistance; whole genome sequencing; pathogenicity Graphical Abstract1. Introduction Infections with Candida species are a severe public health problem across the ...
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus-2) affects the central nervous system (CNS), which is shown in a significant number of patients with neurological events. In this study, an updated literature review was carried out regarding neurological disorders in COVID-19. Neurological...
To date, there are 83 genome assemblies of different strains of Aa deposited in the NCBI database, of which only 12 are complete. The reference genome, encoding 1898 genes, is that of strain VT1169 and has a size of 2.13 Mb (44.4% GC content). It is deposited under the accession ...
Moreover, thanks to the development of technologies for extensive genome sequencing, a wide spectrum of genetic disorders is known nowadays, making the chapter of genetic disorders broader and broader. The pediatrician is not asked to recognize and diagnose all possible genetic syndromes. However, he...
enterica; whole-genome sequencing; wildlife1. Introduction Non-typhoidal Salmonella are important zoonotic bacteria that infect a wide range of domestic and wild animal species and cause salmonellosis in humans [1]. The main reservoir of Salmonella is food-producing animals. However, Salmonella can ...