As known, IFNγ was used as a potent inducer of M1 macrophage phenotype (1). PMA-treated cells were used as controls. The expression of CD68, as general marker of macrophage phenotype, as well as the expression of CD206 and CD204 (scavenger receptor A), as markers of M2 macrophage ...
然而,在与巨噬细胞体外共培养后,两种样本(子宫腺肌病和无病子宫的正位子宫内膜细胞)中IL10基因(通常与M2谱相关)的表达都增加了。同样,另一项研究发现,与对照组相比,“严重”弥漫性子宫腺肌病形式的正位子宫内膜(M2巨噬细胞的marker)中CD163的增加,定义为大部分前壁和/或后壁的广泛结合带增厚。因此,鉴于巨噬...
M1/M2 balance is skewed in sun-exposed aged skin To determine aging-related changes in dermal macrophage phenotypes in sun-exposed skin, we stained human skin tissue samples for CD86, a human M1 macrophage surface marker; CD206, a human M2 macrophage surface marker; and CD68 and CD11b, whic...
(excel at cross- presentation) XCR1 or CLEC9A + cDC2s CD1c + or SIRPα + M1-like CD86 + or CD80 + or iNOS + M2-like CD163 + or CD206 + B Cells CD19 + Naïve IgD + and CD27 – SwitchedMemory Ig D – and CD27 + Unswitched IgD + and CD27 + Activated CD83 + ...
CD163 is the high-affinity scavenger receptor of the hemoglobin–hapto- globin complex, and is a known marker of the monocyte/macrophage lineage17. The phenotype of CD163+ cells is known to resemble alternatively activated, anti-inflammatory M2 macrophages, and several clinicopathologic studies of ...
M1, M2 macrophage phenotypes, tumor-associated macrophages, and two types of myeloid-derived suppressor cells were identified using documented markers from previous studies. Reporting summary Further information on research design is available in the Nature Research Reporting Summary linked to this article...
with either PMA differentiated THP-1 cells or primary human macrophages (differentiated from peripheral blood mononuclear cells by human macrophage colony stimulating factor, M-CSF) and activated by pro-inflammatory stimuli, LPS and IFNγ(M1) and alterna- tive stimuli, IL-4 (M2) respectively....
产品名称: MRP2 (human), mAb (M2II-12) 产品型号: ALX-801-018-C250 产品展商: 瑞士Enzo 产品文档: 无相关文档 简单介绍 MRP2 (human), mAb (M2II-12),产品货号|编号:ALX-801-018-C250,ENZO旗下(Alexis,Biomol,Assay designs,stressgen) MRP2 (human), mAb (M2II-12) 的详细介绍 MRP2 (hum...
Percentages depicted above the marker line indicate the fraction of CCR2-positive cells. To test whether the chemokine released by IIB-MEL-J-MCP-1 was functional, serum-free culture supernatants were seeded in the lower compartment of a chemotaxis chamber. Monocyte/macrophage migration was only ...
Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine and mediator of acute and chronic inflammatory diseases. MIF is overexpressed in various tumours and has been suggested as a molecular link between chronic inflammation and cancer. MIF overexpression is observed in breast cancer but...