INTRODUCTIONHuman embryonic stem cells (hESCs) are derived from pre-implantation blastocysts1 and retain the remarkable ability to differentiate into multiple different tissues2 and to self-renew this property in vitro. These abilities make hESCs very interesting to the scientific and clinical communities...
Embryonic Stem Cells Humanembryonic stem cells(hESCs) exhibit two remarkable properties: the ability to proliferate in an undifferentiated but pluripotent state (self-renewal), and the ability to differentiate into almost all of the specialized cell types in the body(25). They can be isolated by ...
Embryonic Stem CellsThe isolation and culture of human embryonic stem cells (hESCs) has opened up new opportunities not only for regenerative medicine and other biomedical applications but also for the study of early human development, signaling pathway networks and mechanisms of human diseases. ...
此前,研究人员已经利用人胚胎干细胞(human embryonic stem cells,hESCs)诱导培养出人三维类脑(human cortical organoids,hCOs),然而这些hCOs缺乏微脉管系统,无法对深层脑组织提供足够的氧气和营养物质。 近日,来自耶鲁大学干细胞中心的In-Hyun Park研究组利用人类胚胎干细胞建立了具有功能性血管状系统的类脑器官(vascu...
Mesenchymal stem cells (MSCs) have been isolated from many tissues including differentiating human embryonic stem cells (hESCs). Derivation of MSCs from hESCs consists of two major steps: differentiation and isolation. In our hands, differentiation of hESCs towards MSC-enriched culture can be induced...
Human embryonic stem cells (hESCs) have been extensively discussed in public and scientific communities for their potential in treating diseases and injuries. However, not much has been achieved in turning them into safe therapeutic agents. The hurdles in transforming hESCs to therapies start right wi...
Research and biobanking using human embryonic stem cells (hESCs) is a complex and emotional subject to many in research, policy-making and the general public. Holm (2016) presents an overview of debates on the subject within the United Kingdom that reviews issues for consideration when biobanking...
Stem Cells (hESCs) ‹Pluripotent Stem Cell (PSC) Protocols An Introduction to Stem Cell Maintenance Feeder-Dependent Culture of Human Embryonic Stem Cells (hESCs) Feeder-Dependent Culture of Human Induced Pluripotent Stem Cells (hiPSCs) Culturing Human Embryonic...
Since the derivation of human embryonic stem cells (hESCs) from blastocysts in 19981, and the more recent production of human induced pluripotent stem cells (iPSCs) from adult tissues2, anticipation has been growing with regard to their potential as cell therapies for a number of incurable ...
Fig. 1. Cell culture and characterization of immunity-and-matrix regulatory cells (IMRCs). (A) Morphology characteristics of cells at different stages in vitro. hESCs, human embryonic stem cells; hEBs, human embryoid bodies. Scale bars: 200 μm (B) Flow cytometry was used to examine IMRCs...