Embryonic stem cells(ESC) arepluripotent stem cell linesthat have the potential to give rise to virtually every cell type in the body. Yet, unlikeadult stem cells, these cells are not present in the adult organism. In fact, the cellular origin of the ESCs, theinner cell mass(ICM) cells,...
Cell. Mol. Life Sci. 69, 461-470.Steinbeck JA, Koch P, Derouiche A, Brüstle O (2012) Human embryonic stem cell-derived neurons establish region-specific, long-range projections in the adult brain . Cell Mol Life Sci 69 : 461–470...
Here we show that transplantation of ∼750 million cryopreserved human embryonic stem cell–derived cardiomyocytes (hESC-CMs) enhances cardiac function in macaque monkeys with large myocardial infarctions. One month after hESC-CM transplantation, global left ventricular ejection fraction improved 10.6 ...
hES-MP 002.5是从人胚胎干细胞诱导分化而得到的间充质干细胞前体细胞(multipotent mesenchymal progenitors)。hES-MP 002.5与人间充质干细胞(human mesenchymal stem, MS)高度相似,可以分化成为多种中胚层细胞种类。hES-MP 002.5由人胚胎干细胞系SA002.5 ES(a subclone of SA002)分化得来,可以向骨细胞进行高效率的分...
US President Barack Obama has reversed some barriers to human embryonic stem cell research, but much remains to be done to ensure that stem cell research flourishes in the US in the coming decades. In March 2009, President Obama issued an executive order intended to bolster human embryonic stem...
human neural precursor cell References Di Giorgio F, Boulting G, Bobrowicz S, Eggan K . Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation.Cell Stem Cell2008;3: 637–648. ...
Human embryonic stem cells (hESC) have emerged as attractive candidates for cell-based therapies that are capable of restoring lost cell and tissue function. These unique cells are able to self-renew indefinitely and have the capacity to differentiate in
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[2]. Mukhopadhyay M, et al. Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. Developmental Cell. 1 (3): 423–34. [3]. Ou L, et al. Dickkopf Wnt signaling pathway inhibitor 1 regulates the differentiation of mouse embryonic stem cells in vitro and...