The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human Cell Atlas, aims to create a comprehensive reference map of cells during development. This will be critical to understanding normal organogenesis, the effect of mutations, environmental factors and infectious agents on ...
et al. A roadmap for the Human Developmental Cell Atlas. Nature 597, 196–205 (2021). Article ADS CAS PubMed PubMed Central MATH Google Scholar Taylor, D. M. et al. The Pediatric Cell Atlas: defining the growth phase of human development at single-cell resolution. Dev. Cell 49, 10...
et al. A roadmap for the human developmental cell atlas. Nature 597, 196–205 (2021). Article CAS PubMed PubMed Central Google Scholar Girskis, K. M. et al. Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions. Neuron 109, 3239–3251 (2021). Article...
The Human Cell Atlas (HCA) consortium was founded in 2016 with the aim to build a biological atlas of every cell in the human body. Since the release of itswhite paperin 2017, the consortium has grown into a global network of more than 3,600 members in 102 countries, contributing data ...
Wesley, B.T., Ross, A.D.B., Muraro, D.et al.Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.Nat Cell Biol24, 1487–1498 (2022). https://doi.org/10.1038/s41556-022-00989-7 Download citation ...
Emelie Braun and Miri Danan-Gotthold from Sten Linnarsson's group collaborated with the Swedish consortium for theHuman Developmental Cell Atlasto analyze over a million individual cell nuclei from 27 embryos at different stages of development (between five and 14 weeks of fertilization). The study...
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Single-cell transcriptomic atlas of the human retina identifies cell types associated with age-related macular degeneration. Nat. Commun. 10, 4902 (2019). Article Google Scholar Hill, M. C. et al. Integrated multi-omic characterization of congenital heart disease. Nature 608, 181–191 (2022)...
human developmental cell atlas single-cell RNA-sequencing spatial transcriptomics mesenchymal cells stem cells intestinal crypt congenital disease Introduction The intestine is the largest barrier organ in the body, coordinating nutritional requirements and immunity in symbiosis with intestinal microbiota (Soderho...