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The Human Cell AtlasIan A RyerseJamie M HooftDominique P Bureau
Here we created a comprehensive molecular atlas of the human brain vasculature using single-cell RNA sequencing (scRNA-seq) analysis in the developing, adult/control and diseased human brain (Fig. 1a, Extended Data Fig. 1 and Supplementary Methods). We identified extensive heterogeneity among ECs ...
Human cell atlas Non-diseased retina is seldom excised during ocular surgery, so tissue must be obtained postmortem. Given that cell viability declines and transcriptomic profiles change after death, with dramatic alterations after 10 hours post-mortem, data quality hinges in large part on the ti...
Around 5 years ago, Aviv Regev, PhD, realized that it would soon be possible to map all of the cell types in the human body. An atlas of cells across all tissues and organs would undoubtedly advance the scientific community’s understanding of biology and disease and open doors to ...
The entire dataset is available on http://www.macrophages.com/hu-cell-atlas, where a webstart version of BioLayout Express3D enables visualisation of the average expression of each cluster, and the specific expression of individual genes across the dataset. All these data have also been uploaded...
We thus developed a cell atlas in which human and mouse trigeminal ganglia are transcriptionally and epigenomically profiled at single-cell resolution. These data describe evolutionarily conserved and human-specific gene expression patterns within each trigeminal ganglion cell type, as well as the ...
Human Cell Atlas Opens a New Window to Health and Disease An international project is set to detail how every cell type in the body functions BySang Yup Lee To truly, deeply understand how the human body works—and how diseases arise—you would need an extraordinary amount of information. Yo...
Cell Information: Cell Type Fixed Aspect Ratio Colour (Continuous Data): White-Red Blue-Yellow-Red Yellow-Green-Purple Point Size: 03100.511.522.53 Reference: Grubman A., Chew G., Ouyang J.F. et al. A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease ...