The Human Developmental Cell Atlas (HDCA) initiative, which is part of the Human Cell Atlas, aims to create a comprehensive reference map of cells during development. This will be critical to understanding normal organogenesis, the effect of mutations, environmental factors and infectious agents on ...
HumanCellAtlas计划和实现进程总结 人类细胞图谱计划(Human Cell Atlas program)是一个全球合作项目,旨在构建人类身体内所有细胞的分类和组织信息。该计划的目标是创建一个详尽的细胞图谱,以便更好地理解人类身体的生理和病理过程。自从该计划的提出以来,已经取得了重大进展并取得了令人瞩目的成果。 该计划的实施过程非常...
One of the most advanced projects underlying the Human Cell Atlas is the Human Protein Atlas, involving researchers from multiple countries, including Sweden, Denmark, South Korea, China and India. That project, which is continuously updated, offers a glimpse of the kind of work that goes into ...
Human Cortical Cell Atlas v1.0通过单细胞核RNA测序对8个皮层区域进行了非常详细的分析,涵盖了人类新皮层的功能、结构和地形变化范围。这些区域包括初级(运动,M1;躯体感觉,S1;听觉,A1;视觉,V1)和关联脑区(背外侧前额叶皮质,具体为额上回Brodmann区9;前扣带回皮质;颞中回,MTG;角回(angle gyrus, AnG),横跨皮...
In a collection of research articles and related content, the Human Cell Atlas consortium presents tools, data and ideas towards the generation of their first draft atlas of cells in the human body.
In particular, we discuss cell atlases as censuses of cells; as 3D maps of cells in the body, across modalities and scales; as maps connecting genotype causes to phenotype effects; as 4D maps of development; and, ultimately, as foundation models of biology unifying all these aspects and ...
we discuss cell atlases as censuses of cells; as 3D maps of cells in the body, across modalities and scales; as maps connecting genotype causes to phenotype effects; as 4D maps of development; and, ultimately, as foundation models of biology unifying all of these aspects and helping to trans...
Single cell dual-omic atlas of the human developing retina The authors build an atlas of the human retinal development, using approximately 220,000 nuclei from 14 embryos and fetuses (8–23 weeks post-conception). The study reveals major cell classes, key transcription factors, and differences in...
Summary statistics for the Human Commons Cell Atlas can be found here:https://cellatlas.github.io/human
Wesley, B.T., Ross, A.D.B., Muraro, D.et al.Single-cell atlas of human liver development reveals pathways directing hepatic cell fates.Nat Cell Biol24, 1487–1498 (2022). https://doi.org/10.1038/s41556-022-00989-7 Download citation ...