Here, we utilize human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as a model to examine the mechanisms of cardiomyocyte-specific infection by SARS-CoV-2. Microscopy and RNA sequencing demonstrate that SARS-CoV-2 can enter hiPSC-CMs via ACE2. Viral replication and cytopathic ...
cardiomyocyte hPSCs: human pluripotent stem cells hESCs: Human embryonic stem cells RA: Retinoic acid VEGF: vascular endothelial growth factor scRNA-seq: single-cell RNA sequencing ZO-1: zonula occludens-1 TEM: transmission electron microscopy GF: growth factor FGF: fibroblast growth fa...
ASiFnSceuwndeeprrneoviromuoslxyico(b2s0e%rvOed2)thoarthhyApoFxSicar(e1%acOtiv2)atceodnbdyititohnesis(chhAeFmSi-cCeMnvNiorrmono amnednht AanFdS-pCroMmHoyptoe, cardiomyocyte survival in a paracrine manner14, hypoxic preconditioning was used as a working strategy to etteinvirneilcycho; ns...
In vitro matured human pluripotent stem cell-derived cardiomyocytes form grafts with enhanced structure and function in injured hearts. Circulation. 2022;145:1412–26. CAS PubMed Google Scholar Guo Y, Pu WT. Cardiomyocyte maturation: new phase in development. Circ Res. 2020;126:1086–106. CAS...
Cardiac differentiation was induced using the PSC Cardiomyocyte Differentiation Kit (ThermoFisher). Mycoplasma test For the detection of mycoplasma in cell culture we used the EZ-PCR Mycoplasma Test Kit (Biological Industries). Acknowledgments This work was supported by the Leducq Foundation for Cardiovas...
et al. Effects of spaceflight on human induced pluripotent stem cell-derived cardiomyocyte structure and function. Stem Cell Rep. 13, 960–969 (2019). Article CAS Google Scholar Villa-Diaz, L. G., Ross, A. M., Lahann, J. & Krebsbach, P. H. Concise review: the evolution of human ...
Rho-family GTPase 1 (Rnd1) is a biomechanical stress-sensitive activator of cardiomyocyte hypertrophy. J Mol Cell Cardiol. 2019;129:130–43. Article CAS PubMed Google Scholar Meekel JP, Groeneveld ME, Bogunovic N, Keekstra N, Musters RJP, Zandieh-Doulabi B, et al. An in vitro method ...
胚胎干细胞心肌细胞(cardiomyocyte)定向分化试剂盒5次 ELISAKitAHA人抗组蛋白抗体规格:48T/96T 小鼠酪蛋白酶ELISA试剂盒 96T/48T 试剂盒 组装/原装 Human prostate specific aigen (PSA) ELISA Kit 人特异性抗原(PSA)ELISA试剂盒 Humaetinolbindingprotein4,RBP-4ELISAKit 人视黄醇结合蛋白4(RBP-4)ELISA试剂盒 96T...
胚胎干细胞心肌细胞(cardiomyocyte)定向分化试剂盒 5次 胚胎干细胞神经细胞(neuron)定向分化试剂盒 5次 胚胎干细胞内皮细胞(endothelial)定向分化试剂盒 5次 胚胎干细胞造血细? 公司简介 上海西格生物科技有限公司(Shanghai Sig Biotechnology Co., Ltd)是一家生物企业,主要从事免疫学、分子生物学和常规生化试剂的销售...
Lack of robust methods for establishment and expansion of pluripotent human embryonic stem (hES) cells still hampers development of cell therapy. Laminins (LN) are a family of highly cell-type specific basement membrane proteins important for cell adhesi