Take training a machine to recognize dogs for instance: the system must be fed vast numbers of pictures labeled by humans to tell the system which pictures have dogs and which don't. Chen noted the human brain is excellent at processing unknown information with reasoning, but it is still imp...
Network science characteristics of brain-derived neuronal cultures deciphered from quantitative phase imaging data Article Open access 15 September 2020 Versatile live-cell activity analysis platform for characterization of neuronal dynamics at single-cell and network level Article Open access 25 Septembe...
Decision-makers objectively commit to a definitive choice, yet at the subjective level, human decisions appear to be associated with a degree of uncertainty. Whether decisions are definitive (i.e., concluding in all-or-none choices), or whether the under
By transplanting a clump of human brain cells into newborn rats, Stanford University scientists demonstrated that neurons from different species can form connections with one another in a single organism. Their finding lays out a new laboratory model for neuroscience, opening doors for research that ...
Using the GFP-labeled TB40/E virus, we infected human brain organoids at day 45 of differentiation in the presence of different concentrations of the 1B2 or 62-11 antibody (3.2–2,000 ng/mL) and measured GFP fluorescence intensity and brain organoid size for up to 30 days post-infection...
Building a Model of the Living Human Brain Neuromorphometrics provides brain measurement services. Given raw MRI brain scans, we make precise quantitative measurements of the volume, shape, and location of specific neuroanatomical structures. The final measurements result from automated analyses that are...
Human brain development is underpinned by cellular and molecular reconfigurations continuing into the third decade of life. To reveal cell dynamics orchestrating neural maturation, we profiled human prefrontal cortex gene expression and chromatin accessibility at single-cell resolution from gestation to adul...
The specific roles of the Roseburia were further validated by the target bacteria transplantation mouse model, Roseburia intestinalis (Ri.) was gavaged to mice and importantly, it dramatically ameliorated CRS-induced mouse depressive behaviors, increased 5-HT levels in the brain and colon via ...
Results of a Benjamini-Hochberg adjusted Fisher’s combined test. We labeled the top 20 genes with the lowestP-values, genes that were also labeled in (c), and manually labeledTRAF1andJUNB.eConserved Gene Set Enrichment Analysis based on rankings derived from each comparison’s log2fold change...
We found a 1.6-fold greater density of P62+ objects overlapping with particles labeled for the autophagy marker LC3 in C9 versus control astroglia (Extended Data Fig. 4b). This suggested some degree of active autophagy, which was also supported by an unchanged proportion of early and late ...