2021年12月,来自熊本大学等研究机构合作在The Journal of Clinical Investigation发表了“HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/lymphoma”的研究论文。该工作利用单细胞转录组和TCR 测序等技术,证明了人类I型 T 细胞白血病病毒(HTLV-1)可激活 naive T ...
because we are talking about the elimination of HTLV-1, the human T-lymphotropic virus type 1, sometimes called human T-cell leukemia virus. We have been looking after patients with this infection and the consequences for the...
(HBZ), a regulatory protein encoded in the minus strand of the HTLV-1 genome, in the viral pathogenesis. Another paper summarizes the comparative biology of HTLV-1 and HTLV-2. The paper by N. Aliya et al. discusses the possible interplay between HTLV-1 infection and miRNA pathways. Two ...
because we are talking about the elimination of HTLV-1, the human T-lymphotropic virus type 1, sometimes called human T-cell leukemia virus. We have been looking after patients with this infection and the consequences for the last 30 years. We started out with really trying to understand what...
Iwasaki Y (1993) Human T cell leukemia virus type I infection and chronic myelopathy. Brain Pathol 3:1–10 ArticleCAS Iwasaki Y, Sawada K, Aiba I, Mukai E, Yoshida M, Hashizume Y, Sobue G (2004) Widespread active inflammatory lesions in a case of HTLV-I-associated myelopathy lasting 29...
HTLV-1 infections are explicitly found in all the seven aGVHD patients. Furthermore, the multiplex immunohistology (IMC) results confirm that donor-derived CD4+T cells are increased by HTLV-1 infection. Additionally, joint analysis of mass cytometry (CyTOF) and IMC results suggest the aGVHD-speci...
transmission (her mother and/or sibling with HTLV-1 infection) (p = 0.016), age (p = 0.005), Asian maternal race (p = 0.02) and divorced marital status (p = 0.016). The odds ratio of possible protection conferred by cesar- ean delivery did not reach statistical ...
研究人员使用单细胞分析来展示病毒如何过度激活T淋巴细胞,导致其癌变。他们的研究结果发表在《The Journal of Clinical Investigation》上的一篇题为“HTLV-1 infection promotes excessive T cell activation and transformation into adult T cell leukemia/ lymphoma”的文章中。
A method for treating human T cell lymphotrophic virus type 1 infection using an isozyme selective PKC inhibitor, particularly using the isozyme selective PKC inhibitor, (S)-3,4-[N, N'-1,1'-((2''-ethoxy)-3'''(O)-4'''-(N,N-dimethylamino)-... MR Jirousek,DK Ways,LE Stramm - ...
TitleHumanT-cellleukemiavirustype1(HTLV1)infectioninmalignantlymphomasinaHTLV1-endemicarea,Kagoshima,Japan:HTLV-1in-situ-hybridization(ISH)a..