Kinase Regulation Through Dramatic Unfolding, as Told by Hsp90:Cdc37:Cdk4 Atomic Cryoem StructureHsp90 is a ubiquitous ATP-dependent molecular chaperone that accounts for 1–2‥ of the cytosolic proteins and is essential for viability in eukaryotes. It interacts with as much as 10‥ of ...