别名:CDC 37; CDC37_HUMAN; Hsp90 co-chaperone Cdc37; CDC37A; Hsp90 chaperone protein kinase-targeting subunit; p50Cdc37; Hsp90 co-chaperone Cdc37, N-terminally processed; cell division cycle 37, HSP90 cochaperone; P50CDC37;抗体来源:兔克隆类型:多克隆交叉反应:小鼠、人(预测:牛、猪、狗、大...
Hsp90辅助伴侣分子CDC37抗体 供应商 远慕生物别 名 S cerevisiae hypothetical protein CDC37; CDC 37; CDC37 cell division cycle 37 homolog; CDC37 cell division cycle 37 S cerevisiae homolog; Cdc37 homolog; CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone ...
as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis”的研究论文,揭示Hsp90 的Cys521位点起构象开关作用,发生SNO后干扰Hsp90/AHA1的相互作用,促进CDC37的募集,从而...
The co-chaperone p50/Cdc37 is an important partner for Hsp90, assisting in molecular chaperone activities, particularly with regard to the regulation of protein kinases. Analysis of the structure of Hsp90-Cdc37-kinase complexes demonstrates the way in which Cdc37 interacts with and controls the ...
CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc3 ...
CDC37, ID (CDC37, CDC37A, Hsp90 co-chaperone Cdc37, Hsp90 chaperone protein kinase-targeting subunit, p50Cdc37) 供应商 MyBioSource 产品货号 MBS647830 产品报价 ￥询价/0.2mL ￥询价/5x0.2mL ￥询价/其它规格 产品说明书 点击查看 购买方式 ...
2.6 针对Hsp90和其他癌症相关靶点的分子伴侣介导的蛋白质降解剂(chaperone-mediated protein degradation, CHAMP) 2021年,Foley等[92]开发了一种异双功能小分子化合物,即RNK05028(18),通过利用Hsp90结合部分独特的肿瘤选择性药代动力学来实现CHAMP。该化合物由3部分组成,一个目的蛋白的结合剂(BET-结合剂)、一个分子...
CDC37 protein; CDC37_HUMAN; CDC37A; Cell division cycle 37 homolog; Hsp90 chaperone protein kinase targeting subunit; Hsp90 chaperone protein kinase targeting subunit p50Cdc37; Hsp90 chaperone protein kinase-targeting subunit; Hsp90 co chaperone Cdc37; Hsp90 co-chaperone Cdc37; p50; p50Cdc37...
真核生物中,HSP90一般共分子伴侣蛋白CDC91一同发挥作用,促进客户激酶的成熟。Co-IP发现,HSP90和CDC37与v-src互作,但是在HopBF1的IP产物中并没有检测到CDC37(F6B)。沉默CDC37后,影响了HSP90和v-src互作,但不影响HopBF1和HSP90的互作(F6C)。这就说明HopBF1与HSP90互作时并不需要CDC37. ...
The co-chaperone p50/Cdc37 is an important partner for Hsp90, assisting in molecular chaperone activities, particularly with regard to the regulation of protein kinases. The Hsp90/Cdc37complex controls the folding of a large proportion of protein kinases and thus stands at the hub of a multitud...