F. J. Quintana and I. R. Cohen (2008); HSP60 speaks to the immune system in many voices, Novartis Found Symp 291(101‐11; discussion 111‐4, 137‐40.Quintana FJ, Cohen IR (2008) HSP60 speaks to the immune system in many voices. ...
Both of these mediators of stress response are known to play an important role in regulation of neuroendocrine system and immune response. We further demonstrated that ADAPT-232 induced release of Hsp70 is mediated by NPY, suggesting an existence of NPY-mediated pathway of activation of Hsp72 ...
The nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins function as immune sensors in both plants and animals. NLR proteins recognize, directly or indirectly, pathogen-derived molecules and trigger immune responses. To function as a sensor, NLR proteins must be correctly folded...
HSP also play a significant role in helping the immune system recognize diseased cells. During the past three decades, HSP are found to be a potent agent for tumor immunotherapy and studies towards anti-tumor vaccine development still continue today. HSP-based immunotherapies, which could augment ...
aIn addition,it was reported that all HSP patients have IgA1-containing circulating immune complexes of small molecular IgA1-IgG-containing circulating immune complexes of large-molecular-mass. 另外,它被报道所有HSP患者有IgA1包含大分子大量小分子IgA1 IgG包含的流通的免疫复合物流通的免疫复合物。[translat...
aIncreased polymeric IgA production by the mucosal immune system in response to a mucosally presented antigen,such as bacteria,viruses,or fungi,has been hypothesized as a potential mechanism for the development of HSP. 增加的聚合物IgA生产由黏膜免疫系统以回应mucosally被提出的抗原,例如细菌,病毒或者真...
The analysis of cytokine profiles helps to clarify functional properties of immune cells, both for research and for clinical diagnosis. The real-time rever... A Giulietti,L Overbergh,D Valckx,... - 《Methods》 被引量: 3356发表: 2001年 Reproductive factors and breast cancer. PIP: Early age...
Notably, the recombinant AccHsp27.6 protein exhibited significant in vitro molecular chaperone activity and antimicrobial activity. Taken together, these results suggest that AccHsp27.6 might play an important role in the response to abiotic and biotic stresses and in immune reactions. 展开 ...
HSPD1, a nuclear-encoded mitochondrial protein association with co-chaperonin HSP10, helps fold proteins to facilitate degradation of misfolded or denatured proteins, which involved in the activation of the immune system, has pro-inflammatory functions, and has pro-survival or pro-apoptotic roles26....
aAlthough the pathogenic mechanisms of HSPN have not been fully elucidated,perturbations in the immune system,elevations in the serum levels of IgA1,IgA1-containing circulating immune complexes,circulating IgA-rheumatoid factors have been documented for patients with HSP. 正在翻译,请等待... [translate...