结果:hsa-miR-214-3p在宫颈癌细胞中呈高表达;过表达hsa-miR-214-3p后,细胞的增殖和克隆形成能力明显增强(P<0.05);而当抑制内源性hsa-miR-214-3p的表达后,细胞的增殖能力则明显减弱(P<0.001),流式细胞仪检测细胞凋亡结果显示SiHa细胞的凋亡比例明显上升(P<0.05),Western Blot的结果显示Bcl2蛋白的表达显著下降...
Hsa_circ_0065217 silencing reducedin vitroRCC cell-line growth and aggressiveness. Mechanistically, hsa_circ_0065217 promoted alpha protein kinase 2 (ALPK2) expression via its competing endogenous RNA (ceRNA) activity toward miR-214-3p. Moreover, ALPK2 overexpression reversed hsa_circ_0065217 ...
The overexpression of YAP1 reversed the migration, proliferation, and epithelial - mesenchymal transition (EMT) of PC cells and the angiogenic differentiation of HUVECs after miR-214-3p overexpression.Conclusion: Taken together, our study found that hsa_circ_0014784 downregulation decremented invasion, ...
Hsa_circRNA_33287 promotes the osteogenic differentiation of maxillary sinus membrane stem cells via miR-214-3p/Runx3Circular RNAsmiRNAMaxillary sinus membrane stem cellsOsteogenic differentiationBackground: Circular RNAs (circRNAs) comprise a novel class of noncoding RNAs that play important roles in a...
Hsa_circ_0014784-induced YAP1 promoted the progression of pancreatic cancer by sponging miR-214-3pABSTRACTView further author informationQuanjun LinView further author informationFeier ChenView further author informationBo HanView further author information...
Additionally, hsa-miR-214-3p could suppress ATGL. Finally, we show that hsa-miR-214-3p regulates ATGL through the hsa-miR-214-3p/ATGL/PPARα pathway. This study showed that hsa-miR-214-3p-regulates aberrant lipolysis by promoting ATGL expression, which causes AML progression through the PPAR...