MCE 国际站:hsa-miR-149-5p agomir 产品活性:hsa-miR-149-5p agomir 是一种经过特殊化学修饰的miRNA模拟物,miRNA成熟链全链进行甲氧基修饰,在5'端和3'端分别有2个和4个硫代骨架修饰,并在3'端连接有高亲和性胆固醇修饰。miRNA agomir 可以模拟内源性miRNA,上调miRNA活性。与普通模拟物相比,miRNA agomir在动物...
Then, we constructed ceRNA network of circRNA-miRNA-mRNA (IL-6/CCL2/NF-魏B) in AAA and found that hsa_circ_0087352 promotes IL-6 transcription and the secretion of inflammatory cytokines by sponging endogenous hsa-miR-149-5p in macrophages. Dual luciferase reporter gene and RNA pull-down ...