MiRNAs hsa-miR-30a-5p and hsa-miR-99b-5p regulate chemokine-mediated immune response in colorectal cancer.3282-646-2564,3282-206-3896-5046,3,2,38092-21253,38092-21254,2,2Background: The immune response plays a key role in the oncogenesis of colorectal cancer. The heterogeneity of the ...
Wang等[6]研究表明,circRNA-000911在乳腺癌中通过对miR-449的海绵样作用,从而激活Notch1和核因子κB (nuclear factor κB,NF-κB)信号转导通路,发挥其抑制肿瘤的作用。研究[7]报道circ-0068631可通过与EIF4A3结合维持c-myc的稳定性,...
Hsa-miR-194-5p (fold change: -2.628, P < 0.0001) and hsa-mir-195-5p (fold change: -1.584, P < 0.0001) were significantly down-regulated in samples with severe dysplasia compared with controls (Fig. 1a and b). Unsupervised hierarchical cluster analysis revealed that the pattern ...
Figure 5. iMSC exosome rescues the neuronal cell death via hsa-miR-125b-5p mediate Asic1 suppression. A, the experimental diagram to validate the effect of four specific miRNA encapsulated by iMSC exosome against neuron OGD stress. B, cell death rate under the condition: control, OGD, OGD ...
Fig. 5. The mechanism whereby exosomal miR-21 promoted osteoblast proliferation and differentiation. (A) PDCD4 was downregulated by exosomes and miR-21 mimics. (B–F) The regulation of PDCD4 expression via PDCD4-overexpression plasmids and siRNA-PDCD4, and their effects on osteoblastic proliferati...
Li X, Wang C, Chen G, Zou W, Deng Y, Zhou F. EIF4A3-induced circCCNB1 (hsa_circ_0001495) promotes glioma progression by elevating CCND1 through interacting miR-516b-5p and HuR.Metab Brain Dis. 2022;37(3):819–833. doi:10.1007/s11011-021-00899-x ...
何用户阅读,下载,拷贝,传递,打印,检索,超级链接该文献,并为 [23] XU Q, DENG B, LI M, et al. circRNA-UBAP2 promotes the proliferation 之建立索引,用作软件的输入数据或其它任何合法用途. and inhibits apoptosis of ovarian cancer though miR-382-5p/PRPF8 版权转让:文章出版前全体作者与编辑部签署了...
(Fig. 9B) Following that, the DEC-FImiRNA-hub gene network was constructed, including two circRNAs (hsa_circ_0070934 and hsa_circ_0004315) and three miRNAs (hsa-miR-511-5p, hsa-miR-214-3p, and hsa-miR-424-5p) and hub genes (Fig. 9C)....
Silencing of miR-17-5p suppresses cell proliferation and promotes cell apoptosis by directly targeting PIK3R1 in laryngeal squamous cell carcinoma. Cancer Cell Int. 2020;20:14. 16. Luo M, Sun G, Sun JW. MiR-196b affects the progression and prognosis of human LSCC through targeting PCDH-17....
To explore the downstream mechanism of hsa_circ_0001394, we used Circular RNA Interactome (https://circinteractome.nia.nih.gov/) to predict 6 miRNAs (context + score percentile ≥ 96), including miR-527 (99′), miR-518a-5p (99′), miR-370 (97′), miR-885-3p (97′), ...