英文名称:hsa-miR-9-5p mimic 品牌厂商性质产地货期价格 MedChemExpress (MCE)生产商美国现货￥960 性能特点 hsa-miR-9-5p mimic 是一种化学合成的miRNA模拟物,能模拟内源性miRNA,上调miRNA活性,用于功能获得性(gain-of-function)研究。 在线咨询 询底价 ...
miR-9-5pmimic与pcDNA-TGFBR2单独或一起转染鼻咽癌细胞,蛋白质印迹检测TGFBR2的表达;细胞计数实验(CCK8)检测细胞活力;体外侵袭实验(transwell)检测细胞侵袭能力;划痕试验检测细胞迁移能力.结果 miR-9-5p mimic能明显抑制鼻咽癌CNE1细胞中TGFBR2的表达(P<0.01);野生型TGFBR2报告载体与miR-9-5p mimic共转后,细胞...
并进一步鉴定出hsa-miR-4639-5p的核心启动子区域位于MYLIP翻译起始位点上游的-560至-275区域;敲除miR-4639-5p核心启动子后,hsa-miR-4639-5p前体及成熟体mRNA均下降,DJ-1蛋白水平升高,细胞抗氧化能力和细胞活力增强。
Hsa_circ_0037128 aggravates high glucose-induced podocytes injury in diabetic nephropathy through mediating miR-31-5p/KLF9 Rong Fang, Xiangchang Cao, Yaping Zhu & Qiming Chen Pages 254-263 | Received 04 Nov 2021, Accepted 30 Jan 2022, Published online: 14 Mar 2022 Cite this article https:...
Hsa_circ_101555 functions as a competing endogenous RNA of miR-597-5p to promote colorectal cancer progression. Oncogene. 2019;38:6017–34. Article CAS PubMed Google Scholar Cheng Z, Yu C, Cui S, Wang H, Jin H, Wang C, et al. circTP63 functions as a ceRNA to promote lung ...
Hsa_circ_0063329 inhibits prostate cancer growth and metastasis by modulating the miR-605-5p/tgif2 axis Daojun Lv, Shengren Cen, Shuxin Yang, Zihao Zou, Jianfeng Zhong, Zhaojun Pan, show all Pages 1101-1115 | Received 21 Dec 2022, Accepted 25 Jan 2023, Published online: 05 Feb...
Expression and possible role of hsa-miR-582-5p/bta-miR-582 microRNA in granulosa cells of bovine ovarian follicles 来自 ResearchGate 喜欢 0 阅读量: 10 作者:A Zielak-Steciwko,J Browne,P Mcgettigan,M Gajewska,A Evans 摘要: Lactation in dairy cattle is associated with a multitude of ...
Abstract We011: The role of hsa-miR-9-5p in hypercontractility: insights from patients with hypertrophic cardiomyopathyHypertrophic cardiomyopathyGene mutationsStem cell biologyBackground: Hypertrophic cardiomyopathy (HCM) is an inherited disease characterized by the thickening of the heart muscle. Mutations...
Effects of hsa-miR-9-3p and hsa-miR-9-5p on Topoisomerase IIβ Expression in Human Leukemia K562 Cells with Acquired Resistance to Etoposidedoi:10.1096/fasebj.2022.36.S1.R3696DNA topoisomerase IIα (TOP2α/170; 170kDa) and Topoisomerase IIβ (TOP2β/180; 180kDa) are important targets ...
Conversely, K/VP.5 cells transfected with miR-9-3p/5p inhibitors led to increased TOP2 beta/180 protein without a change in TOP2 beta/180 mRNA and resulted in enhancement of XK469-induced DNA damage. Taken together, these results strongly suggest that TOP2 beta/ 180 mRNA is ...