HPV-associated diseasesSuzana Ljubojevic, MD, PhD ⁎ , Mihael Skerlev, MD, PhDDepartment of Dermatology and Venereology, University Hospital Center Zagreb, School of Medicine University of Zagreb,Zagreb, CroatiaAbstract Nearly 200 distinct human papilloma viruses (HPVs) have now been recognized, ...
HPV represents the most common sexually transmitted infection worldwide. Around 200 different genotypes exist. They are distinguished into low- and high-risk genotypes, depending on the risk of such HPV-associated lesions undergoing malignant transformation. The high-risk genotypes include HPV 16 and ...
health. Given that the incidence of and mortality from HPV-associated cancers remain strongly associated with the socioeconomic status of individuals and the human development index of countries, elimination efforts are unlikely to succeed unless prevention efforts focus on health equity, with a commitme...
HPV-associated malignancies include cervical, vulvar, vaginal, penile, oropharyngeal, anal, and rectal cancers. There was an overall increase in HPV-associated cancer incidence, from 10.8 per 100,000 persons during the period 2004-2008 to 11.7 per 100,000 persons during 2008-2012. In terms of ...
Human papillomavirus (HPV)-positive (HPV+) oropharyngeal squamous cell carcinoma (OPSCC) has one of the most rapidly increasing incidences of any cancer in high-income countries. The most recent (8th) edition of the UICC/AJCC staging system separates HPV
HPV-associated alteration of cervical microbiome and host metabolome in Xichang, China was identified through 16S ribosomal RNA gene (16S rRNA) sequencing and untargeted metabolomics. The results would help to reveal the association of altered cervical microbes and serum metabolites with the HPV ...
HPV-associated cancers. The longer half-life of integrated viral transcripts compared to episomal transcripts is believed to promote cellular immortalization and transformation1. Thus, HPV integration is considered a major driving factor in HPV-associated carcinogenesis. Frequent disruption of the HPVE2...
HPV vaccine mandatesSchool-entry requirementsHighlights•Brief description of HPV-associated oropharyngeal cancer disparities.•Highlights current evidence which suggest that existing HPV vaccines may well prevent HPV-associated oropharyngeal cancer.•Discusses value of mandating HPV vaccine as a school ...
HPV-associated cancers. The longer half-life of integrated viral transcripts compared to episomal transcripts is believed to promote cellular immortalization and transformation1. Thus, HPV integration is considered a major driving factor in HPV-associated carcinogenesis. Frequent disruption of the HPVE2...
Human papillomavirus (HPV) is a pervasive sexually transmitted infection associated with various cancers, including cervical, anogenital, and oropharyngeal carcinomas. While the majority of HPV infections are transient and self-limiting, persistent infections with high-risk HPV strains play a critical role...