根据HPV病毒基因E6、E7和L1基因序列可对HPV进行基因分型。目前已发现超过200种HPV型别,根据致宫颈癌和癌前病变的相关性,可以把HPV分为高危型(high-risk)和低危型(low-risk)。 常见的有 高危型:HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66,...
1.Zhang JJ, Zhao YQ, Dai Y, Dang L…QiaoYL, Lang JH, et.al. Effectiveness of High-risk Human Papillomavirus Testing for Cervical Cancer Screening in China: A Multicenter, Open-Label, Randomized Clinical Trial. JAMA Oncology. 2021,...
[8] Junji Zhang, Yuqian Zhao, Yi Dai, et al. Effectiveness of High-risk Human Papillomavirus Testing for Cervical Cancer Screening in China: A Multicenter, Open-label, Randomized Clinical Trial[J]. JAMA Oncology. 2021, 7(...
INTRODUCTION: High-risk human papillomavirus (hrHPV) testing is expected to replace cytology as primary screening method for cervical cancer screening in an increasing number of countries. The high sensitivity of hrHPV testing is combined with a limited specificity which makes triaging of hrHPV posit...
Methods From August 2017 to March 2018, 1107 physicians were invited to return cytobrushes used during routine Pap screening to the Cervical Cancer Screening Laboratory for HPV testing. Only age or year of birth was collected. Specimens were screened for high-risk HPV (hrHPV) and positive ...
MEDICAL screeningNearly all cervical cancers are caused by persistent high-risk human papillomavirus (hrHPV) infection. There are 14 recognized hrHPV genotypes (HPV 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68), and hrHPV genotypes 16 and 18 comprise approximately 66...
The vast majority of HPV infections go away without causing health problems. But high-risk strains of HPV can cause changes in your cells that can turn into cervical cancer, especially if the virus stays in your body for 10 to 20 years and you’re a woman or person with a cervix who ...
Which high-risk HPV assays fulfil criteria for use in primary cervical cancer screening? Several countries are in the process of switching to high-risk human papillomavirus (hrHPV) testing for cervical cancer screening. Given the multitude of a......
Screening tests for anal cancer are not routinely recommended for all people. Still, some experts recommend anal cytology testing (also called an anal Pap test because it's much like the Pap test used for cervical cancer) for people at higher risk of ...
[1] Zhao,Y., et al. Real-world effectiveness of primary screening with high-risk humanpapillomavirus testing in the cervical cancer screening programme in China: anationwide, population-based study. BMC Med 19, 164 (2021).https://doi.org/10.1186/s12916-021-02026-0 ...