•LC-MS•LC／MSDTRAP系统概述 •MassSpectrometer MassSpectrometerBlockDiagram HighVacuumSystem Inlet Ionsource MassAnalyzer Detector DataSystem MassSpectrometerBlockDiagram HighVacuumSystem Turbomolecularpumps Inlet Ionsource MassAnalyzer Detector DataSystem Inlet HighVacuumSystem Inlet Ionsource MassAnalyzer D...
2 Cluster analysis diagram for 15 batches of samples content determination results 已基本能反映不同批次样品的主要特征,模型的累 积解释率 RXcum2 为 0.962,累积预测能力 QXcum2 为 0.864,均大于 0.5,提示 PCA 模型的区分度和预测 程度都较好.得出的 PCA 得分图见图 3,24 种化学 成分的载荷图见图 4....
图4 PF573228 肝微粒体体外代谢的代谢途径示意图 Fig. 4 The schematic diagram for the metabolic pathway of PF573228 with liver microsome in vitro 参 考 文 献 [1] Li S F,Hua Z C ,FAK expression: regulation and therapeutic potential[J]. Adv Cancer Res,2008,101: 45-61. ...
Then STRING was applied to build the network of PPI, and Bioconductor database was used to perform GO and KEGG enrichment analysis, and Cytoscape software was used to build the drug component-target-pathway-disease network diagram Core targets were then ...
Fig. 3. Venn diagram of the total sea cucumber samples in Dalian area. Note: By using a Venn diagram that incorporates multiple comparative groups of differentially expressed metabolites, we can visually compare the shared (overlap) and unique (unique) differentially expressed metabolites between diff...
2 Venn diagram of drug target and inflammation target 3.2.3 PPI 网络及核心靶点 通过 Venn 分析获得 的 87 个重叠靶点上传到 STRING 数据库,进行蛋 白互作网络的构建,隐藏游离靶点,最终得到 85 个 靶蛋白节点,864 条边的 PPI 网络模型.同时,保存 TSV 格式文件,将其导入到 Cytoscape 3.9.1 软件 中进行...
Prediction database,association network diagram was drawn in combination with Cytoscape 3.8.2,the gene ontology function enrichment analysis and Kyoto Encyclopedia of Gene and Genome pathway enrichment analysis on the core target gene were conducted,so that the component-target-pathway network diagram ...
The Venn diagram of the components found in each SHL preparation form Full size image Table 2 The common chemical components identified with names and formulas in all three SHL preparation forms Full size table A comparison of the components identified in SHL oral liquid done in the current work...
2 Venn diagram of intersection targets of drugs and diseases 图 3 药物与疾病交集靶点 PPI 分析 Fig. 3 PPI analysis of intersection targets of drugs and diseases gamma,PPARγ),谷胱甘肽硫转移酶 P1(glutathione S-transferase pi-1,GSTP1),IL-1β,核受体亚家族 3C 组成员 2(nuclear receptor ...
1 BPI diagram of positive ion and negative ion of SHD 表 2 SHD 的 UPLC-Q-TOF-MS/MS 定性分析结果 Table 2 UPLC-Q-TOF-MS/MS qualitative analysis results of SHD 峰号 tR/ 离子模式 min 化合物名 实测值 理论值 误差 分子式 (m/z) (m/z) (×10−6) 碎片离子 (m/z) 来源 化合物类型...