Hari Prasad, Patel, Vijaysree, Suresh and Ranjith: Simultaneous estimation of metoprolol tartrate and chlorthalidone by using RP-HPLC and method development as per ICH guidelines. Der Pharma Chemica, vol. 5(5):
Mirabegron and tamsulosin have recently been prescribed to men with overactive bladder for the treatment of benign prostatic hypertrophy. An efficient and environmentally friendly HPLC method was developed to accurately measure the levels of mirabegron a
HPLC, method development and validation, prulifloxacinPrulifloxacin is the lipophilic prodrug of ulifloxacin [1], is an oral fluoroquinolons with a broad spectrum in vitro activity against various Gram-positive and Gram-negative microorganisms. It inhibit Topoisomerase...
Method was validated for accuracy, precision, linearity, specificity and sensitivity in accordance with International Conference on Harmonisation guidelines. Validation studies revealed that the method is specific, accurate, precise, reliable and reproducible. Good linear correlation coefficient (rsup2 /sup ...
The method was found, however, to be very sensitive to the pH of the mobile phase buffer. The method was successfully validated following the guidelines of the International Conference on Harmonization (ICH). This validation proved that the method was suitable for the determination of CHX and ...
Submission Guidelines Editorial Board Details Submit manuscript Development and application of a high-performance liquid chromatography diode-array detection (HPLC–DAD) method for the simultaneous quantification of phenolic compounds in the aerial part of Glehnia littoralis Download PDF Article...
A new method using high-performance liquid chromatography coupled with ultra violet detection (HPLC–UV) was developed and validated for the simultaneous quantification of atazanavir, dolutegravir, darunavir, efavirenz, etravirine lopinavir, raltegravir, rilpivirine and tipranavir in human plasma. For the...
Development of a RP-HPLC Method for Simultaneous Determination of Reference Markers used for in-situ Rat Intestinal Permeability Studies Introduction Pre-formulation studies performed on the development of pharmaceutical dosage forms require the knowledge of two key components of the active ingredients; the...
3.2. Method Validation The process of demonstrating, through laboratory testing, that the characteristic parameters of a method meet the requirements of the intended analytical application is known as method validation. According to ICH guidelines, the validation of an HPLC method includes testing for ...
The result obtained shown that the method best fits for estimation of drug in capsule formulation and thus can be used for its routine analysis. The newly developed method was validated according to the ICH guidelines with respect to specificity, linearity, accuracy, precision and robustness....