How to Develop Validated HPLC MethodsRachel Muenz
In recent years, conventional chemistry techniques have faced significant challenges due to their inherent limitations, struggling to cope with the increas
Whether you’re entering the scientific equipment space as a new entrepreneur or expanding your background in lab services, this guide offers a complete roadmap to help you build and grow a successful lab supply company. This is an in-depth guide with many important details to consider along ...
all necessary method descriptions, validation reports, and justification of specifications. Understanding the breadth of responsibility to act as the SPOC will drive the choice for the company. This in turn will help the monograph elaboration process to run more smoothly because there should be better...
Under a Creative Commons license Open accessTwo different workflows were tested in order to develop methods that provide deeper insight into the secreted O-glycoproteome. Bovine serum samples were subjected to lectin affinity-chromatography both at the protein- and peptide-level in order to selectively...
Zhao et alCitation149 also exploited the self-assembly properties of simvastatin to develop a fibrin-targeted delivery system for co-delivering simvastatin and ticagrelor. Both in vitro and in vivo experiments demonstrated that the nanoparticle drug delivery system exhibited good stability, reduced off-...
In addition, access to suitable equa- tions could allow one to directly link the network properties to those of a single (average) nanoparticle-junction pair. As we will show, such a link allows the development of new methodologies to analyse junctions. In this work, we develop a simple ...
-free lifetime was responsible for the increased aggressive feature of survival cells to perform rapid 3-dimensional migration during the first 3 h of a transwell assay, no significant influence was observed with 2-dimensional surface migration detected at 12 and 24 h by a wound-healing method....
How did your research in this area start and what led you to develop these methods? Coupling HPLC to ICP has been widely described. This hyphenation can supply a lot of information. Many laboratories that have an ICP instrument use it to perform elemental analyses. However, this instrumen...
“a process of quickly identifying known chemotypes”, dereplication is today a not so univocal concept and has evolved over the last years in different ways. The present review covers all dereplication-related sudies in natural product research from 1990 to 2014. Its writing brought to light ...