X-rays have been pivotal in research involving quantum mechanics theory, crystallography and cosmology. In the industrial world, X-ray scanners are often used to detect minute flaws in heavy metal equipment. And X-ray scanners have become standard equipment in airport security, of course. The X...
X-rays have been pivotal in research involving quantum mechanics theory, crystallography and cosmology. In the industrial world, X-ray scanners are often used to detect minute flaws in heavy metal equipment. And X-ray scanners have become standard equipment in airport security, of course. The X...
The X-Ray View of the Low-Mass Stars in the Solar Neighborhood We present the results of a complete and sensitive X-ray survey of all known stars of spectral type K and M in the immediate solar vicinity with distances ... JUERGEN H. M. M. SCHMITT,THOMAS A. FLEMING,MARK S. GIAMPAPA...
How to grow crystals for X‐ray crystallographydoi:10.1107/S2053229624006624Sommer, Roger D.Acta Crystallographica Section C: Structural Chemistry
Watching DNA polymerase η make a phosphodiester bond. Nature 487, 196–201 (2012). A breakthrough in studying phosphodiester bond formation was achieved with the use of a revised method of time-resolved X-ray crystallography. Monitoring this reaction revealed the role of a third metal ion in ...
Another pioneer of early X-ray crystallography of proteins was William T. Astbury (1898 − 1961, Fig. 5) in Leeds, also a physicist originally, who investigated both proteins and nucleic acids. In the early 1930s this field of research was so sparsely populated that the two British ...
Cell signalling X-ray crystallography Surface receptors 1. Introduction Vaccinia virus (VACV), the smallpox vaccine, is the prototype member of the Orthopoxvirus genus of the Poxviridae: a family of large, complex dsDNA viruses that replicate in the cytoplasm of host cells and form virions with...
The results also show that the contribution of phenotypic screening to the discovery of first-in-class small-molecule drugs exceeded that of target-based approaches — with 28 and 17 of these drugs coming from the two approaches, respectively — in an era in which the major focus was on ...
X-rays have been pivotal in research involving quantum mechanics theory, crystallography and cosmology. In the industrial world, X-ray scanners are often used to detect minute flaws in heavy metal equipment. And X-ray scanners have become standard equipment in airport security, of course. The X...
Here we present the crystal structure of the DDB1–DCAF1–HIV-1–Vpr–uracil-DNA glycosylase (UNG2) complex. The structure reveals how Vpr engages with DCAF1, creating a binding interface for UNG2 recruitment in a manner distinct from the recruitment of SAMHD1 by Vpx proteins. Vpr and Vpx...