provided.For example, the present disclosure features an administration regimen relating to an antisense compound described herein to rapidly achieve and maintain higher antisense compound concentrations in patients with spinal muscular atrophy (SMA), and to further improve the efficacy of the treatment....
“The best care providers... will collaborate with you to decide upon the best option for your family.” John Brandsema, MD Understanding the facts about SMA and how to treat it can help you make better decisions about your child’s care. Knowing what to expect might also help you feel...
12 CT imaging can identify (1) LRV compression between the aorta and SMA; (2) a “beak sign” of a triangular shape at the narrowing of the LRV at the aortomesenteric space, conferring 91.7% sensitivity and 88.9% specificity16; (3) LRV diameter ratio (comparing the hilar diameter to ...
it combined in cartilage cells to the promoter region of COL2A1 COL11A2, ACAN, and CDRAP for promoting cartilage formation [73]. SOX9 exerts a VC-inhibiting effect because SOX9 binds directly to RUNX2's runt domain and inhibits RUNX2 function by its evolutionarily conserved high-mobility grou...
buyer personas as a foundational component of effective marketing. Ask an industry thought leader, and you will hear similar validation, “personas are more important than ever” and “know your buyer first.” In fact, 73% of companies currently use, or plan to use, buyer personas (ITSMA)....
Drugs that treat high blood pressure, high cholesterol and heart disease are currently being investigated to treat eye diseases associated with heart disease. Blood pressure control is beneficial to decreasing the risk of eye disease. In fact, the American Diabetes Association has included in its cur...
Natural Way to Treat Asthma With Unani Medicine Often referred to as an Arabian or Islamic medicine, as it was once used by the Arabs and the Mughals in India, Unani medicine refers to the natural ways of treating a disease. Following a humoral theory of the presence of four ...
Enlarged poresare often associated withoily skin, butdry skin typescan experience them, too. Because it can be tricky to treat this combination of skin concerns, we consulted withDr. Peter Schmid, a SkinCeuticals ambassador and plastic surgeon based in Colorado, to find out thebest skincare pro...
Objectives The field of pain psychology has taken significant steps forward during the last decades and the way we think about how to treat chronic pain has radically shifted from a biomedical perspective to a biopsychosocial model. This change in perspe
Our adaptable ‘SHOW RESPECT’ framework covers (1) Supporting and preparing trial participants to receive results, (2) HOw will the results reach participants?, (3) Who are the trial participants?, (4) REsults—what do they show?, (5) Special considerations, (6) Provider—who will share ...