对于HCT后的分子学复发,目前没有标准治疗;但人们现在普遍认识到,一旦出现复发性突变或 T 细胞嵌合体水平下降,预后就会很差,从而强调了针对这些情况采取新方法的必要性。作者优先考虑将高复发风险患者(HCT前MRD+,高危基因组学)纳入预处理强化、移植后维持、使用围移植...
The rationale behind this advice is that the most common species within a genus is in general the most virulent one and, hence, what is appropriate to treat this organism is likely also appropriate for infections caused by other species with similar susceptibility patterns in vitro from that ...
LOW-DOSE ALEMTUZUMABHIGH-RISKREDUCED-INTENSITYPERIPHERAL-BLOODT-CELLSAlthough allogeneic hematopoietic cell transplantation (HCT) is currently the standard curative treatment for acute leukemia, relapse remains unacceptably high. Measurable (minimal) residual disease (MRD) after allogeneic HCT may be used as...
Diuretics(sometimes called water pills) work to lower blood pressure by decreasing the amount of fluid inside the blood vessels. The most common type of diuretic used to treat hypertension is thiazide diuretics, such as: Hydrochlorothiazide Chlorthalidone These medicines help the body get rid of extr...
In this review, we summarize the current progress made in customized microalgae-based biomaterials that can be used to develop therapeutics to treat ODAD (Figure 1). Information on different microalgal genera and their unique properties are presented, and relevant examples from the literature are ...
Low blood pressure, Drowsiness Weakness Abnormal taste (metallic or salty taste) Increased uric acid levels Sun sensitivity Increased BUN andlevels to subside, and if one ACE inhibitor causes cough it is likely that the others will too.
Mature B cell neoplasms, previously indolent non-Hodgkin lymphomas (iNHLs), are a heterogeneous group of malignancies sharing similar disease courses and treatment paradigms. Most patients with iNHL have an excellent prognosis, and in many, treatment can
to treat a variety of infectious diseases. This may explain the high resistance rates registered inS. suisisolates in last two decades (Figure1A). For example, tylosin (Tylan) has been extensively used as growth promoter, and this could be related to high macrolide resistance rates observed. Al...
S. Food and Drug Administration (FDA) approved 45 novel drugs, including four used to treat multiple myeloma5. About a decade ago, most chemotherapies were limited to conventional pan-cytotoxic drugs that targeted DNA or microtubules such as the CHOP regimen (cyclophosphamide, hydroxydaunorubicin, ...
The therapeutic vaccine is being studied nowadays for all virus-causing cancers, as it is designed to treat an existing condition like MCC by triggering the immune system to perceive and attack specific cells or proteins linked with diseases such as MCC [178]. IL-12 is an important cytokine ...