Effective treatments for lowering serum TG levels include lipid-lowering drugs, insulin, heparin, low-molecular heparin, and blood purification techniques, including haemoperfusion, plasma exchange, and continuous renal replacement therapy [12, 13]. However, standardized guidelines for the treatment of H...
Standardized monitoring of BCR::ABL1 mRNA levels is essential for the management of chronic myeloid leukemia (CML) patients. From 2016 to 2021 the European Treatment and Outcome Study for CML (EUTOS) explored the use of secondary, lyophilized cell-based
In cases like this, therapeutic phlebotomy is used to help prevent organ rejection. The procedure and goals are largely the same as for polycythemia vera, with the aim of reducing HCT to normal levels. How Therapeutic Phlebotomy Is Done Therapeutic phlebotomy can be performed at a blood donor c...
Cancer is caused by a combination of genetic and epigenetic abnormalities. Current cancer therapies are limited due to the complexity of their mechanism, underlining the need for alternative therapeutic approaches. Interestingly, combining the Clustered
(B) Serum EPO levels after 2 weeks of treatment (2 and 6 h after the final dose). (C) Hematocrit (Hct) levels before and after treatment with molidustat. Creatinine clearance, urine volume, and BUN levels were measured as renal functional parameters (Fig. 3). Adenine treatment reduced ...
European Centre for Disease Prevention and Control EWS: Ewing’s sarcoma GCT: Germ cell tumor HCC: Hepatocellular carcinoma HCT: Hematopoietic cell transplantation IFO: Ifosfamide LCH: Langerhans histiocytosis MTX: Methotrexate NAT: Nucleic acid testing ...
2007). Another promising property of quercetin is that it increased levels of claudin-4. This protein is part of the tight junctions responsible for barrier function of epithelial cells. Hence, quercetin may have a positive effect on preventing intestinal barrier disruption, which seems to play an...
Interestingly, the category of removing toxin did not account for the predominant relation with the length of hospital stay from the result of multiple linear regression analysis, showing the therapeutic methods were primarily attributed to ISRD rather than removing toxin. The results indicated the func...
[111,224]. Consequently, combining ferroptosis inducers represents a novel approach to combat sarcoma resistance to chemotherapeutic agents like cisplatin. For instance, the combination of the ferroptosis agonist erastin with cisplatin has demonstrated a significant synergistic effect against A549/HCT116 ...
Trabedersen (OT-101/AP 12009) is an antisense oligonucleotide that blocks the mRNA of human transforming growth factor beta 2 (TGF-β2), a protein that is required for viral replication. Xiong et al. showed that high TGF-β levels in patients with COVID-19 could lead to ARDS and Kawasa...