Intermediate molecules, particularly oligonucleotides having an oligonucleotide, an azide functionality oligonucleotides with alkyne functionalities, grafted, oligonucleotide microarray containing them, as well as in cell targeting purposes and biological research, they The use of oligonucleotides grafted. None [...
To achieve this goal, the researchers took advantage of the versatility of syntheticDNAoligonucleotides and of the predictability of DNA-DNA interactions. “Synthetic oligonucleotides are amazing molecules, they can be modified with a range of reactive groups and also with recognition elements that can ...
The assay probes are target-specific antibodies conjugated to oligonucleotides through a biotin–streptavidin linkage. Each oligonucleotide in the pair presents a 5′ or 3′ end; these are brought into proximity when the antibodies on the assay probes bind to two diff...
We also highlight recent studies showing that discrete populations of neurons that synthesize NO in the hypothalamus constitute integrative systems that support life by relaying metabolic and gonadal signals to the neuroendocrine brain, and thus gate the onset of puberty and adult fertility. The putativ...
The assay is based on gold nanoparticles coated with thiol-modified antisense oligonucleotides (ASOs), specific for the N gene of SARS-CoV-2, capable of diagnosing positive cases in 10 min. According to the study, changes in surface plasmon resonance observed using a UV–vis spectrophotometer ...
W. Evidence for a physiological role for nitric oxide in the regulation of the LH surge: effect of central administration of antisense oligonucleotides to nitric oxide synthase. Neuroendocrinology 64, 449–455 (1996). Article CAS PubMed Google Scholar d'Anglemont de Tassigny, X. et al. ...
However, other studies that used shorter oligonucleotides showed that a RecA filament is not required for TLS (Schlacher et al., 2005). The study by Schlacher et al. (2005) also suggests that two molecules of RecA bound to Pol V in the presence of DNA are minimally necessary to catalyze...
Growth of the system occurs with the involvement of templates (short prebiotic oligonucleotides) that increase probability of PDE bond formation. The growing peptide constantly participates in the formation of the system: if the latest Aa to join the peptide increases the probability of next progene ...
On the contrary, it must be difficult to synthesize hydrocarbons with immature [GADV]-proteins. It is considered that the selective synthesis of [GADV]-amino acids by immature [GADV]-proteins, which was performed before cell structure formation, further advanced the steps to the emergence of ...