How strong is the evidence that antibiotic use is a risk factor for antibiotic-resistant, community-acquired urinary tract infection? Journal of Antimicrobial Chemotherapy 50, 241-7.Hillier SL, Magee JT, Howard AJ, Palmer SR. How strong is the evidence that antibiotic use is a risk factor for...
The increasing number of antibiotic-resistant bacteria worldwide has become a major public health threat. Discovery and study of different bacterial resistance strategies as well as the development of new antimicrobial compounds, which are also able to overcome the protecting outer-membrane barrier of G...
Advanced brain signals-reading headset have been in development for a while, and it is currently possible to 'read' a patient's emotional state – something that can provide great assistance in therapy. Elon Musk and his company Neuralink want to take it a step further. Musk suggests that ...
The peptide antibiotic microcin B17 induces double-strand cleavage of DNA mediated by E. coli DNA gyrase. EMBO J. 10, 467–476 (1991). Article PubMed PubMed Central Google Scholar Hegde, S. et al. A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA. Science ...
The Chemistry between Us One of the best well-described methods where a small compound triggers protein dimerization involves rapamycin, a macrolide antifungal antibiotic from Streptomyces hygroscopicus. Originally, rapamycin was found to form a functional complex with the FKBP protein (FK50...
For a temperature cut-point of >38.0°C sensitivity was 0.64 (95% CI 0.59–0.69) and specificity was 0.81 (0.80–0.82) to identify bacteraemic patients. Conclusion One third of the acute medical bacteraemic patients had a normal temperature at arrival to the MED. A normal temperature combin...
Gut dysbiosis occurs when the balance of bacteria in the gut becomes imbalanced because there is not the ideal number of good or bad bacteria or a combination of the two. It can happen for a variety of reasons, including due to diet, stress, antibiotic use, or as a result of illnesses....
Prudent use of antibiotics requires antibiotic susceptibility testing. Susceptibility profiles of EUM. hyorhinisstrains are shown in Table 2. Low and narrow minimum inhibitory concentration (MIC) ranges were found for tiamulin, independent of the country of origin, which indicates a high sensitivity of...
The GMF is also important for the functioning of multicellular organism (Fesenko et al.2010; Mo2012; Bertea et al.2015). For instance, cardiovascular and nervous systems have been proven to be most sensitive to changes in the magnetic field.This sensitivity of the cardiovascular system can be ...
The presence of cysts can obstruct urinary flow and create environments conducive to bacterial growth. Antibiotics are effective treatments and are required to prevent recurrent infections. However, adverse effects of frequent antibiotic use include the development of antibiotic resistance, destruction of ...