Proposes an approach to encoding that will allow genomics companies to make DNA sequences available to the public while retaining some intellectual property protection. DNA sequence back-translation; Copyright infringement.StemmerWillemP.C.EBSCO_AspNature Biotechnology...
Process of copying a segment of DNA sequence into an RNA molecule. This process can be divided in three steps: initiation, elongation and termination. Histone Family of positively charged proteins that associate with DNA and help condense it into chromatin. Hypotonic shocks Refer to an environmental...
The fundamental question of how sequence defines conformation is explicitly answered if the structures of all possible sequences of a macromolecule are determined. We present here a crystallographic screen of all permutations of the inverted repeat DNA sequence d( CCnnnN6N7N8GG), where N6,N7, an...
The following examples demonstrate how to usebedtools getfastato extract DNA sequences and other information from the FASTA file. Extract the sequence from the BED file (default behavior)Permalink The following example shows how to usebedtools getfastato extract DNA sequences from the genomic coordin...
RNA molecules can fold into intricate shapes that can provide an additional layer of control of gene expression beyond that of their sequence. In this Review, we discuss the current mechanistic understanding of structures in 5′ untranslated regions (UTRs) of eukaryotic mRNAs and the emerging metho...
"Short palindromic repeats" refers to sequences that read the same forward and backward, like the words "kayak" and "racecar."DNAconsists of two paired strands twisted around each other in a helix. A DNA palindrome thus refers to a string of DNA letters, or bases — A (adenine), C (...
PulseNet uses DNA fingerprinting of bacteria making people sick to detect thousands of local and multistate outbreaks around the United States. Through this network, state public health laboratories and other collaborators share PFGE results of STEC and other bacterial pathogens to better identify ...
The sensors are polymer nanoparticles coated in DNA barcodes, short DNA sequences that are unique and easy to identify. The researchers engineered the particles to be targeted by protease enzymes linked to stage I lung adenocarcinoma. Upon contact, the proteases cleave off the barcodes, w...
Topoisomerase activity is indispensible to cells, but requires the transient breakage of DNA strands. This property has been exploited, often for significant clinical benefit, by various exogenous agents that interfere with cell proliferation. Despite decades of study, surprising findings involving ...
This gene plays an essential role in prokaryotic life; it is ubiquitous to all bacteria, and its DNA sequence is characterized by both highly conserved and variable regions, which allows distinguishing among species. For this reason, it is used as a sort of molecular fingerprint for assigning ...