Proposes an approach to encoding that will allow genomics companies to make DNA sequences available to the public while retaining some intellectual property protection. DNA sequence back-translation; Copyright infringement.StemmerWillemP.C.EBSCO_AspNature Biotechnology...
The field of molecular epidemiology is very promising, as sophisticated techniques are being developed to address etiology, genetic susceptibility and mechanisms for induction of disease. The use of biomarkers plays a key role in these investigations because the information can be used to predict the ...
This data set includes a unique set of amphimorphic sequence, those that crystallize in two different conformations and serve to bridge the three structural phases. We have thus constructed a map of DNA structures that can be walked through in single nucleotide steps. Finally, the resulting data...
Germ cells are the only cells in the body capable of giving rise to a new organism, and this totipotency hinges on their ability to assemble membraneless germ granules. These specialized RNA and protein complexes are hallmarks of germ cells throughout their life cycle: as embryonic germ granules...
complex to translate the mRNA code into an amino acid sequence, a protein. DNA is made up of a sequence of nucleotide bases. The four bases are adenine, thymine, guanine and cytosine. The sequence in which these bases occur on a strand of DNA ultimately codes for the production of certain...
a single primer, polymerase, and a DNA template, chain-terminated, end-labeled fragments representing each base in a segment of DNA can be generated and subsequently read as a sequence. This is known as cycle sequencing, since the fragments are genera...
bedtools getfastais a command-line utility for extracting DNA sequences from the reference FASTA file based on the genomic coordinates given in the BED/GFF/VCF file format. The general syntax ofbedtools getfastalooks like this: # defaultbedtoolsgetfasta-fireference.fasta-bedregions.bed-fooutput....
"Short palindromic repeats" refers to sequences that read the same forward and backward, like the words "kayak" and "racecar."DNAconsists of two paired strands twisted around each other in a helix. A DNA palindrome thus refers to a string of DNA letters, or bases — A (adenine), C (...
sequencing by CE is used to determine the specific base sequence of a particular fragment or gene segment, this technique can also provide sizing, relative quantitation, and genotyping information for fluorescently labeled DNA fragments produced by PCR using primers des...
Process of copying a segment of DNA sequence into an RNA molecule. This process can be divided in three steps: initiation, elongation and termination. Histone Family of positively charged proteins that associate with DNA and help condense it into chromatin. Hypotonic shocks Refer to an environmental...