This affords better defined and more reproducible mucin substrates (e.g. mucin produced by intestinal organoids and sophisticated analytical methods; see below). 5. Novel methods, models and technologies to investigate the GI mucus, glyco-code, and bacterial interaction 5.1. Chemical and biophysical...
But in order to make the project a success, the right technology was needed. “At that point in time, it became obvious to me that we needed to engage other partners in developing plates for those systems. And that'...
"By screening ten different type of cells and organoids, we found that lung, colon, heart, liver, and pancreatic organoids and dopamine neurons can be infected by SARS-CoV-2," says Dr. Chen. "This work presented the first stem cell model to understand the which organs and cells within ...
To help with these studies, Yilmaz’s lab has developed a way to use mouse or human intestinal stem cells to generate miniature intestines or colons in cell culture. These “organoids” can then be exposed to different nutrients in a very controlled setting, allowing researchers to analyze how...
Today's technologies offer tremendous opportunities for authors to make their out-of-print or otherwise unavailable books more widely available. Some authors want to revive their books by creating e-books, while others may want to use print-on-demand technology or deposit their books in openly ac...
Advances in stem-cell technology, such as the development of urine-derived stem cells and stem-cell-derived organoids, offer new opportunities for overcoming current challenges. These problems may be solved by improving the innate regenerative capacities of renal progenitors, strategically increasing the...
This approach may even elucidate the nature and evolution of consciousness as a manifestation of the cellular continuum from unicellular to multicellular life. We need such a functional genomic mechanism for the process of evolution if we are to make progress in biology and medicine." John S. ...