Homocysteine is a naturally-occurring amino acid found in blood plasma. High levels of homocysteine in the blood are believed to increase one’s risk of heart disease, stroke, Alzheimer’s disease, and osteoporosis. Symptoms of B12 deficiency include: Fatigue Low mood or personality/mood changes ...
Increased exposure is in theory possible via TDM but concerns were raised because (a) evidence is lacking (apart from PK/PD data suggesting a relationship between exposure and outcome), (b) it takes time to increase exposure and TDM is not always available in a timely fashion and (c) ...
Ashwagandha is also sold in western markets as a food supplement to increase energy and endurance [202]. The main biologically active chemical constituents of WS are alkaloids (isopelletierine, anaferine, cuseohygrine, anahygrine, etc.), steroidal lactones (withanolides and withaferins), and ...
The conceptualization of the ecosystem's actors and engagement touch points can contribute to stakeholder identification and selection in order to better manage relationships and to increase service efficacy and effectiveness. Thus, managers can foster actors' participation by developing integrated strategies...
Using ex vivo IFN-γ Elispot assays, they investigated the functionality of DENV-specific memory T cell responses in 338 individuals from Sri Lanka, who were naturally infected and were either hospitalized due to dengue or had mild or sub clinical dengue infection. The results suggested that the...
As anticipated earlier, in an effort to increase in vivo expansion and anti-tumor activity, second/third generation CARs have been developed. However, it is anticipated that the infusion of second/third generation CAR T-cells might associate with an increased risk of toxicity, due to superior ...