Rare mutations have been proposed to restrict the development of broadly neutralizing antibodies against HIV-1, but this has not been explicitly demonstrated. We hypothesized that such rare mutations might be identified by comparing broadly neutralizing and non-broadly neutralizing branches of an antibody...
First, BG created short summaries of each transcript and pulled direct quotes from each transcript and generated a prelimi- nary descriptive code list. Three authors (BG, LS, KEH) read nine initial transcripts and revised these codes iteratively [24]. BG and ST applied these codes to the ...
To analyze the data, we used the M-GTA (Kinoshita,2003), which was developed on the basis of methodology that was formulated by Glaser and Strauss (1967) on the GTA. When using the M-GTA, data analysis is conducted in several stages. Initially, the transcript of one of the participants...
First, a main data analyst read through four interviews and applied the start list codes to segments of text. This analyst created new codes based on emergent topics relevant to the main research questions or that were repeated in the transcript or across transcripts. Then, a second analyst ...
education sciences Article How to Align the University Curricula with the Market Demands by Developing Employability Skills in the Civil Engineering Sector Livia Anastasiu 1,*, Alexandra Anastasiu 2, Mihaela Dumitran 1, Codru¸ta Crizboi 1, Alexandra Holmaghi 1 and Maria Nicoleta Roman 1 1 ...
viruses Review How Polyomaviruses Exploit the ERAD Machinery to Cause Infection Allison Dupzyk 1 and Billy Tsai 2,* 1 Department of Microbiology and Immunology, University of Michigan Medical School, 1150 West Medical Center Drive, Ann Arbor, MI 48109, USA; adupzyk@umich.edu 2 Department of ...
For comparison, each human cell is estimated to have ~3 million molecules of Pol ε and 500,000 molecules of Pol δ, based on the abundance of the catalytic subunits [47]. Additionally, unlike replicative polymerases and PCNA which increase transcript and protein just before S-phase, Y-...