The association of exposure to asbestos with development of mesothelioma has been demonstrated in the seminal experimental work of Wagner in the 1960s [1]. In 1987, Kane and co-workers [2] observed that already a single dose of asbestos fibers damages the mesothelium tissue and stimulates rege...
after a fasting period, lipogenesis increases rapidly and occurs primarily in the liver20,21, with several enzymes likely being crucial to this process both in the liver and in the adipose tissue. The acetyl-CoA carboxylase
(2014) Tissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for cancer medicine?. Expert Review of Molecular Diagnostics 14 , 853-869 /Lorenzo F, Sempere. (2014) Tissue slide-based microRNA characterization of tumors: how detailed could diagnosis become for ...
“We built a database that says, ‘Here are all of the different cells that the mRNA could be delivered to, and here are all of their microRNA signatures,’ and then we use computational tools andmachine learningto differentiate the cells,” Becraft explains. “For instance, I need to m...
To detect active substances present in very small quantities in the extracts, a concentration step is usually required and is based on evaporation of the solvent in vacuo. It is advised to extract and evaporate at low temperature not to destroy any thermolabile constituent. Unfortunately, this conc...
Prior to a BMA, the patient’s general dental practitioner is suitable to extract a tooth. After receiving a BMA, a dentist, oral surgeon (or maxillofacial surgeon) is the most appropriate [109]. Do all patients need antibiotics? For patients with a previous or current history of BMAs and...
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection Front. Med., 14 (2020), pp. 185-192 Google Scholar [63] J. Shang, G. Ye, K. Shi, Y. Wan, C. Luo, H. Aihara, Q. Geng, A....
The immune system is a complex network of specialized cells that work in concert to protect against invading pathogens and tissue damage. Imbalances in this network often result in excessive or absent immune responses leading to allergies, autoimmune dis
The tumour suppressor gene TP53 is mutated in ~50% of human cancers. In addition to its function in tumour suppression, p53 also plays a major role in the response of malignant as well as nontransformed cells to many anticancer therapeutics, particularly
The findings could also point to a treatment for fibrosis when scarring doesn't stop when it should, causing an overgrowth and hardening of scar tissue. Finally, the researchers found a pathway that governs the proper alignment of intestinal smooth muscle with neighboring lacteal cells, which is...