"This RNA is in a 'double-stranded' form, called 'dsRNA', that is not normally found in our body. Human cells have evolved ways to detect dsRNA as a warning sign of an active viral infection and, in this way, dsRNA acts as an important trigger for cells to mount an anti-viral immu...
Due to unequal crossing-over and gene conversion, nuclear rRNA genes undergo rapid concerted evolution by repairing mismatches among recombining chromosomes. This promotes intragenomic homogeneity of the repeat units and maintains intragenomic uniformity. Moreover, ITS is easy to detect from small ...
Firstly, the reference sequence of the mature miRNA is localized on the pre-miRNA and then all other molecules that map to a defined region comprising miRNA site can be explored to detect all types of 3′ and 5′ offset and modified sRNAs thus allowing a precise isomiR classification. Some ...
Parallel computation of genome-scale RNA secondary structure to detect structural constraints on human genome. BMC Bioinf. 2016;17(open in a new window)(1(open in a new window)):203. doi: 10.1186/s12859-016-1067-9 (Open in a new window)PubMed(Open in a new window)Google Scholar...
cytoplasm. Those interested in more details of these receptors and their role in the immune response are invited to consult the work of [185]. From the perspective of this paper, however, the major point is that RIG-I recognises short dsRNA as well as ssRNA with a 5′-triphosphate group,...
While the cell attempts to detect and eliminate foreign invasive nucleic acids, the virus manipulates the cell's gene expression pathways for many purposes. Many viruses attempt to hijack the cellular machinery to translate their own messages rather than cellular messages in an effort to maximize ...