How to Detect Apoptosis - The Scientist - Magazine of the Life SciencesJeffrey M. Perkel
To investigate whether the detection of apoptosing retinal cells (DARC) could detect cells undergoing apoptosis in a laser model of retinal damage.Laser le... S Schmitz-Valckenberg,G Li,A Maass,... - 《Investigative Opthalmology & Visual Science》 被引量: 110发表: 2008年 ...
As a testament to the efficiency and rapidity of efferocytosis, it is surprisingly difficult to histologically detect apoptotic cells despite 4109 cellular suicides occurring per day in adult tissues.15,16 There are several broadly defined phases of phagocytic clearance of apoptotic cells: (1) Find-...
A routine monitoring of serum ferritin and TSAT is recommended to detect and treat ID, although most results about iron laboratory parameters derive from expert recommendations or reviews and clinical impact is not well studied [5]. Diagnosis of ID in quiescent IBD can be made by serum ferritin...
are able to identify and kill cancerous cells without the need to detect MHC receptors. Once they target one of these cells, Cytotoxic T cells use perforins, granzymes, and proteases, or even FAS ligand signaling to trigger the caspase cascade and induce apoptosis in the unhealthy cell. Both...
The final chapter is a review of two nuclear-based techniques, positron emission tomography and single-photon emission computed tomography, imaging methodologies to detect the loss of neurons, monitor the progression of the disease and validate the neuroprotective potential of therapeutic strategies. All...
Most of the time, cells are able to detect and repair DNA damage. If a cell is severely damaged and cannot repair itself, it undergoes so-called programmed cell death or apoptosis. Cancer occurs when damaged cells grow, divide, and spread abnormally instead of self-destructing as they should...
Both cancer and fibrosis are diseases involving dysregulation of cell signaling pathways resulting in an altered cellular microenvironment which ultimately leads to progression of the condition. The two disease entities share common molecular pathophysiology and recent research has illuminated the how each pr...
What do you do if your protein of interest has a similar molecular weight as the loading control protein you want to detect? Easy! Just select antibodies that are produced in different host species. The host species can be found on every CST®antibody datasheet and web page by looking up...
(2024) detect that OsGRP3/OsGRP162 transmits diurnal signals downstream of EC, regulating the diurnal thermotolerance of rice. In order to better explain the thermomorphogenesis of rice, we extend this concept to the morphogenesis of plant architecture, floral organs, and caryopses under heat ...