[1,4] Moreover a structural similarity between the [beta]-lactam ring and the inhibitory neurotransmitter [gamma]-aminobutyric acid (GABA) contributes to a decrease in normal GABA inhibition, allowing excitatory impulses to potentiate seizure-like activity. [1,5,...
Methamphetamine: Methamphetamine use can result in severe dryness of the eyes and corneal damage. Additionally, this drug often leads to extreme dilation of the pupils, which increases sensitivity to light and can strain the optic nerve. Chronic methamphetamine abuse is also linked to neurotoxicity th...
Mussels exposed to each concentration were maintained under two temperatures, 17 and 21°C, which represent actual and predicted warming conditions, respectively. After 28 days, oxidative stress status, metabolism related parameters, neurotoxicity and histopathological alterations were measured. The results ...
a form ofhemoglobinthat doesn’t effectively transfer oxygen to the cells, into normal hemoglobin. Methylene blue is also used off-label to treatencephalopathy(brain disease) from neurotoxicity caused by ifosfamide, a chemotherapy drug.
Acetylcholinesterase inhibitors used in treatment of Alzheimer's disease prevent glutamate neurotoxicity via nicotinic acetylcholine receptors and phosphat... We show here that donepezil, galanathamine and tacrine, therapeutic acetylcholinesterase inhibitors currently being used for treatment of Alzheimer's di...
3 Mitigating long-term post–COVID-19 cognitive, emotional, and behavioral sequelae would decrease disease burden. COVID-19 neuropathology may serve as a model for deciphering neurodegenerative processes related to neuroinflammation in other brain diseases and developing new treatment strategies. Back to...
This regimen did not cause any major neurotoxicity in treatment-naive patients, thereby avoiding a side effect that would substantially affect quality of life in elderly patients.50 With regard to rituximab/chemotherapy particularly, the DRC regimen described above is highly attractive as it combines ...
[16]. Air pollution-related neuroinflammation has been associated with neurotoxicity, oxidative stress, and impaired control of inflammatory processes [17,18]. The developing brain is particularly vulnerable to toxicants during two critical developmental periods, the foetal and early life, due to the ...
and reducing oxidative stress as neurotoxic effects of PPA.#This study demonstrates that various probiotics protect gut barrier function and could be used to alleviate increased intestinal permeability caused by oxidative stress and impaired GABA signaling as a result of PPA neurotoxicity, addressing the...
Besides, it has been hypothesized that the decrease in the intestinal bacteria leads to an increase in opportunistic pathogens; this might explain the increase in mortality in GLY-exposed bees [34]. Other studies have demonstrated that the maternal behaviour of rats exposed to GLY was altered. ...