In the case of the spectrin and α-actinin subgroup of the family, the α-helical repeats position two actin-binding modules correctly to form bundles or networks. Despite the importance of the dimerization process, relatively little is known about the interactions that occur between subunits. The...
Water is the most-studied molecule in all of science. It is a simple molecule, consisting of just one oxygen atom and two hydrogen atoms. It is one of the easiest atoms to build a model of, and is therefore an excellent starting point for students learning to build molecular models. Step...
Today, chocolate is everywhere: From hot chocolate to rich truffles, we all have our favorite way to eat or drink it. But chocolate has changed dramatically since its beginnings in South America, and scientific inventions along the way have played a critical role in shaping it into the modern...
While an alliance approach can help shrink the innovation deficit, pressure to dowill accelerate as patents expire in 2025-2026. The years 2020 and 2021 have seen the lowest M&A in terms of value in the last several years while, a company's capacity to fund transactions based on the stren...
“Our mission is to democratize science for everyone,” she says. “GPT-4 is a very large language model and it runs on a lot of resources. In our pursuit of democratizing access, we want to build smaller models that learn from GPT-4 and can also learn to...
Murine genetic models of human disease focused around the use of embryonic stem cells, it is now theoretically possible to model the genetic lesion underlying any human disease in the mouse. ... AR Clarke - 《Current Opinion in Genetics & Development》...
Here, we explore how to build a simulation app for reflective metalens design, which can easily be compiled into a standalone app. Solving the Superconductor Teaching Challenge with Apps March 13, 2023 Superconductors can be a challenging subject to teach. Explore how a professor is addressing th...
The stalked jellyfish (Staurozoa) is an extraordinary clade within medusozoan cnidarians in which the medusa is attached to the substrate unlike the pelagic jellyfishes which compose the rest of the medusozoans. Along with this remarkable feature, staurozoans are characterized by an extremely low...
Using 3D models of the parts of plant and animal cells can help students to understand the cell from a visual perspective. To represent both the mitochondria, also known as the "powerhouse" of the cell" and the the chloroplast, organelles found only in plant cells and eukaryotic algae, use...
5a). To build the model (Fig. 3a–f), we docked modules from the assembled CCW pose as rigid bodies into the CW maps. Linkers between domains were then built manually. Fig. 3: The CW pose of the switch. a–e, Individual folds of the C-ring subunits in the CW pose: FliF (a),...