Knowledge graphs give multidirectional insight into drugs, diseases and targets to accelerate drug repurposing—but organizations must address key questions
Further information can be found in Research Analysis Platform documentation: https://dnanexus.gitbook.io/uk-biobank-rap/working-on-the-research-analysis-platform/using-spark-to-analyze-tabular-data Notebook file: A103_Export-participant-data_Python.ipynb Dependency A Spark instance Run info: run...
These Genome-Wide Association Studies, or GWAS, analyze the entire genome of a large number of individuals to identify genetic variants associated with a clinical outcome, such as the ability to naturally control viral replication. Measuring HIV replication control: not enough in African populations T...
many analysis platforms cannot accurately interrogate the region due to the technical challenges of assessing GC-rich DNA content. Therefore, it is important that fragile X carrier screening is being performed with robust technology that can analyze extreme ...
useful for further analyses and necessary for creating input files for tools like PLINK and REGENIE. Further information can be found in Research Analysis Platform documentation:https://dnanexus.gitbook.io/uk-biobank-rap/working-on-the-research-analysis-platform/using-spark-to-analyze-tabular-data ...
At first, these newer, larger studies seemed to be meeting with some success. With massive amounts of data at one’s fingertips, a strong belief in one’s cause and the ability to analyze data in any number of ways, one is able to make some statistical correlation...
There is a growing gap between the generation of massively parallel sequencing output and the ability to process, analyze and interpret the resulting data. New users of sequencing technologies are left to navigate a bewildering maze of base calling, alignment, assembly and analysis tools. Many softw...
High-throughput sequencing, next generation sequencing (NGS), has, indeed, the potential to bypass some of the shortcomings of GWAS. The availability of this huge amount of data does not correspond to a simpler and more efficient way to discover genetic variants associated with the phenotype. To...
useful for further analyses and necessary for creating input files for tools like PLINK and REGENIE. Further information can be found in Research Analysis Platform documentation:https://dnanexus.gitbook.io/uk-biobank-rap/working-on-the-research-analysis-platform/using-spark-to-analyze-tabular-data ...